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DAX01

Sigma-Aldrich

AIM Biotech 3D Cell Culture Chips

Synonym(s):
Microfluidic chips

material

plastic

sterility

sterile

packaging

box of 25 ea Individually packed sterile chips

availability

not available in South Korea, Singapore

Application

An easy-to-use, modular platform to co-culture different cell types in discrete 3D and 2D compartments.
Applications include angiogenesis, vasculogenesis, metastasis (spheroid dispersion, intra- & extravasation), immuno-oncology (immune checkpoint, T-cell killing efficiency), 3D culture of tumor spheroids/ biopsies/ organoids, and other organotypic models.

Features and Benefits

  • Microscope slide format 75 mm × 25 mm
  • Compatible with all polymerizable gels including collagen, fibrinogen, Matrigel, etc. and combinations thereof
  • Gas permeable laminate for effective gas exchange
  • Optically clear and compatible with phase contrast, fluorescence and confocal microscopy
  • Enables monotypic or organotypic co-culture models
  • Enables the control of interstitial flow across the 3D gel region
  • Enables the control of chemical gradients across the 3D gel region
  • Sterile & ready-to-use
  • Designed for rapid media exchange through vacuum aspiration with no risk of over-aspiration
  • Designed for modular expansion with AIM Luer Connectors
  • Fits into AIM Microtiter Plate Holders for easy handling and stacking

Certificate of Analysis

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Certificate of Origin

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Product Information Sheet

Quotes and Ordering

Articles

Create a 3D kidney nephrotoxicity model on the AIM Biotech 3D cell culture chip

AIM Biotech’s easy-to-use modular platform for conducting 3D cell culture into your research. The AIM Biotech organ-on-a-chip enables you to run simple assays or create more complex microphysiological systems. The versatile platform is suitable for a wide variety of cell types and is customizable for your specific needs.

Human Renal Proximal Tubule Epithelial Cells (RPTEC) as an Essential Advanced Model to Express Kidney Drug Transporters and Toxicity

Human renal proximal tubule epithelial cells (RPTECs) are commonly used to predict human renal drug permeability and to investigate drug efflux. We have generated transporter knockout (KO) cell lines using CompoZr® Zinc Finger Nuclease (ZFN) technology in a proprietary renal proximal tubule epithelial cell line.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service