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MilliporeSigma

E1904

Sigma-Aldrich

Ethyl-3,4-dephostatin

>99% (HPLC), solid

Synonym(s):

3,4-Dihydroxy-N-ethyl-N-nitrosoaniline

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1 MG
$222.00

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About This Item

Empirical Formula (Hill Notation):
C8H10N2O3
CAS Number:
Molecular Weight:
182.18
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77

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Quality Level

assay

>99% (HPLC)

form

solid

color

brown

solubility

DMSO: soluble 22 mg/mL
H2O: soluble 8 mg/mL

storage temp.

2-8°C

SMILES string

CCN(N=O)c1ccc(O)c(O)c1

InChI

1S/C8H10N2O3/c1-2-10(9-13)6-3-4-7(11)8(12)5-6/h3-5,11-12H,2H2,1H3

InChI key

ZTXUSFPBLYQDDN-UHFFFAOYSA-N

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This Item
M9440N0912S5192
form

solid

form

powder

form

solid

form

solid

assay

>99% (HPLC)

assay

>98% (HPLC)

assay

≥98% (TLC)

assay

≥98% (HPLC)

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

solubility

DMSO: soluble 22 mg/mL, H2O: soluble 8 mg/mL

solubility

DMSO: soluble 18 mg/mL, H2O: insoluble

solubility

DMSO: soluble 28 mg/mL, H2O: soluble

solubility

DMSO: soluble ~28 mg/mL, H2O: insoluble

color

brown

color

red-brown

color

white

color

light yellow

Biochem/physiol Actions

Stable analog of dephostatin. Selective inhibitor of protein tyrosine phosphatase 1B and SHPTP-1. Does not inhibit CD45-associated phosphatases.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Tyrosine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Store under nitrogen

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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J H Kim et al.
Cell death & disease, 4, e588-e588 (2013-04-13)
Hypoxia enhances the proliferation and migration of adipose-derived stem cells (ASCs) via the generation of reactive oxygen species (ROS). Therefore, this study primarily investigated whether or not ROS generation could regulate microRNA-210 (miR-210) expression, and increase proliferation/migration of ASCs. In

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