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Ethylenediaminetetraacetic acid tetrasodium salt hydrate


EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate hydrate
Linear Formula:
CAS Number:
Molecular Weight:
380.17 (anhydrous basis)
EC Number:
MDL number:
PubChem Substance ID:

Quality Level

biological source

synthetic (organic)






Insoluble matter, passes filter test


11.0-12.0 (0.1 M in H2O)


H2O: 0.1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.01%

cation traces

Al: ≤0.001%
As: ≤0.0001%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: <0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%


≤0.06 at 280 in H2O at 0.1 M
≤1.5 at 260 in H2O at 0.1 M

storage temp.

room temp

SMILES string




InChI key


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EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood.

Preparation Note

Soluble in water at room temperature up to 1.45 M. The pH of this solution will be approximately 10 to 11 and will be rather viscous.

Signal Word


Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2

Target Organs

Respiratory Tract

Storage Class Code

11 - Combustible Solids



Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Certificate of Origin

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