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MilliporeSigma

EHU000811

MISSION® esiRNA

targeting human IFNGR1

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$242.00

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$435.00

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCCACAGGTCCCTGTTTTTACCGTAGAGGTAAAGAACTATGGTGTTAAGAATTCAGAATGGATTGATGCCTGCATCAATATTTCTCATCATTATTGTAATATTTCTGATCATGTTGGTGATCCATCAAATTCTCTTTGGGTCAGAGTTAAAGCCAGGGTTGGACAAAAAGAATCTGCCTATGCAAAGTCAGAAGAATTTGCTGTATGCCGAGATGGAAAAATTGGACCACCTAAACTGGATATCAGAAAGGAGGAGAAGCAAATCATGATTGACATATTTCACCCTTCAGTTTTTGTAAATGGAGACGAGCAGGAAGTCGATTATGATCCCGAAACTACCTGTTACATTAGGGTGTACAATGTGTATGTGAGAATGAACGGAAGTGAGATCCAGTATAAAATACTCACGCAGAAGGAAGATGATTGTGACGAGATTCAGTGCC

Ensembl | human accession no.

ENSG00000027697

NCBI accession no.

NM_000416

shipped in

ambient

storage temp.

−20°C

Quality Level

100

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MISSION® esiRNA targeting human IFNGR1

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Ensembl | human accession no.

ENSG00000027697

Ensembl | human accession no.

ENSG00000108679

Ensembl | human accession no.

ENSG00000171855

Ensembl | human accession no.

ENSG00000180353

Gene Information

human ... IFNGR1(3459), IFNGR1(3459)

Gene Information

human ... LGALS3BP(3959), LGALS3BP(3959)

Gene Information

human ... IFNB1(3456), IFNB1(3456)

Gene Information

human ... HCLS1(3059), HCLS1(3059)

esiRNA cDNA target sequence

GCCACAGGTCCCTGTTTTTACCGTAGAGGTAAAGAACTATGGTGTTAAGAATTCAGAATGGATTGATGCCTGCATCAATATTTCTCATCATTATTGTAATATTTCTGATCATGTTGGTGATCCATCAAATTCTCTTTGGGTCAGAGTTAAAGCCAGGGTTGGACAAAAAGAATCTGCCTATGCAAAGTCAGAAGAATTTGCTGTATGCCGAGATGGAAAAATTGGACCACCTAAACTGGATATCAGAAAGGAGGAGAAGCAAATCATGATTGACATATTTCACCCTTCAGTTTTTGTAAATGGAGACGAGCAGGAAGTCGATTATGATCCCGAAACTACCTGTTACATTAGGGTGTACAATGTGTATGTGAGAATGAACGGAAGTGAGATCCAGTATAAAATACTCACGCAGAAGGAAGATGATTGTGACGAGATTCAGTGCC

esiRNA cDNA target sequence

AATTCCACACTGTGCCCTTCCAGTTGCTGGCCCGGTACAAAGGCCTGAACCTCACCGAGGATACCTACAAGCCCCGGATTTACACCTCGCCCACCTGGAGTGCCTTTGTGACAGACAGTTCCTGGAGTGCACGGAAGTCACAACTGGTCTATCAGTCCAGACGGGGGCCTTTGGTCAAATATTCTTCTGATTACTTCCAAGCCCCCTCTGACTACAGATACTACCCCTACCAGTCCTTCCAGACTCCACAACACCCCAGCTTCCTCTTCCAGGACAAGAGGGTGTCCTGGTCCCTGGTCTACCTCCCCACCATCCAGAGCTGCTGGAACTACGGCTTCTCCTGCTCCTCGGACGAGCTCCCTGTCCTGGGCCTCACCAAGTCTGGCGGCTCAGATCGCACCATTGCCTACGAAAACAAAGCCCTGATG

esiRNA cDNA target sequence

TCCTCCAAATTGCTCTCCTGTTGTGCTTCTCCACTACAGCTCTTTCCATGAGCTACAACTTGCTTGGATTCCTACAAAGAAGCAGCAATTTTCAGTGTCAGAAGCTCCTGTGGCAATTGAATGGGAGGCTTGAATACTGCCTCAAGGACAGGATGAACTTTGACATCCCTGAGGAGATTAAGCAGCTGCAGCAGTTCCAGAAGGAGGACGCCGCATTGACCATCTATGAGATGCTCCAGAACATCTTTGCTATTTTCAGACAAGATTCATCTAGCACTGGCTGGAATGAGACTATTGTTGAGAACCTCCTGGCTAATGTCTATCATCAGATAAACCATCTGAAGACAGTCCTGGAAGAAAAACTGGAGAAAGAAGATTTCACCAGGGGAAAACTCATGAGCAGTCTGCACCTGAAAAGATATTATGGGAGGATTCTGCATTACCTGAAGGCCAAGGA

esiRNA cDNA target sequence

CATGGCCACTTTGGACTCTTCCCTGCAAATTATGTCAAGCTTCTGGAGTGACTAGAGCTCACTGTCTACTGCAACTGTGATTTCCCATGTCCAAAGTGGCTCTGCCTCCACCCCCTCCCTATTCCTGCTGCAAATGTCTAACCAGATGAGGTTCTGGACAGACTTCCCTCTCCTGCTTCATTAAGGGCTTGGGGCAGAGACAGCATGGGGAAGGAGGTCCCCTTCCCCAAGAGTCCTCTCTATCCTGGATGAGCTCATGAACATTTCTCTTGTGTTCCTGACTCCTTCCCAATGAACACCTCTCTGCCACCCCAAGCTCTGCTCTCCTCCTCTGTGAGCTCTGGGCTTCCCAGTTTGTTTACCCGGGAAAGTACGTCTAGATTGTGTGGTTTGCCTCATTGTG

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

NCBI accession no.

NM_000416

NCBI accession no.

NM_005567

NCBI accession no.

NM_002176

NCBI accession no.

NM_005335

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Chunxiao Lv et al.
The Journal of pharmacology and experimental therapeutics, 376(1), 21-28 (2020-11-08)
Immune checkpoint inhibitors have emerged as a frontline treatment of a variety of malignancies. However, only a subset of patients respond to these therapies, and many initial responders eventually develop resistance, leading to tumor relapse. Programmed death protein 1 is

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