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MilliporeSigma

EHU039711

Sigma-Aldrich

MISSION® esiRNA

targeting human SLC1A1

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$242.00
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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

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description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

CTTGGTTCGAGAACACAGCAACCTCTCAACTCTAGAGAAATTCTACTTTGCTTTTCCTGGAGAAATTCTAATGCGGATGCTGAAACTCATCATTTTGCCATTAATTATATCCAGCATGATTACAGGTGTTGCTGCACTGGATTCCAACGTATCCGGAAAAATTGGTCTGCGCGCTGTCGTGTATTATTTCTGTACCACTCTCATTGCTGTTATTCTAGGTATTGTGCTGGTGGTGAGCATCAAGCCTGGTGTCACCCAGAAAGTGGGTGAAATTGCGAGGACAGGCAGCACCCCTGAAGTCAGTACGGTGGATGCCATGTTAGATCTCATCAGGAATATGTTCCCTGAGAATCTTGTCCAGGCCTGTTTTCAGCAGTACAAAACTAAGCGTGAAGAAGTGAAGCCTCC

Ensembl | human accession no.

ENSG00000106688

NCBI accession no.

NM_004170

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... SLC1A1(6505), SLC1A1(6505)

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MISSION® esiRNA targeting human SLC1A1

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MISSION® esiRNA targeting human SLC1A2

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MISSION® esiRNA

MISSION® esiRNA targeting human SLC1A3

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EHU010991

MISSION® esiRNA

MISSION® esiRNA targeting human SLC11A1

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EHU091701

MISSION® esiRNA

Gene Information

human ... SLC1A1(6505), SLC1A1(6505)

Gene Information

human ... SLC1A2(6506), SLC1A2(6506)

Gene Information

human ... SLC1A3(6507), SLC1A3(6507)

Gene Information

human ... SLC11A1(6556), SLC11A1(6556)

esiRNA cDNA target sequence

CTTGGTTCGAGAACACAGCAACCTCTCAACTCTAGAGAAATTCTACTTTGCTTTTCCTGGAGAAATTCTAATGCGGATGCTGAAACTCATCATTTTGCCATTAATTATATCCAGCATGATTACAGGTGTTGCTGCACTGGATTCCAACGTATCCGGAAAAATTGGTCTGCGCGCTGTCGTGTATTATTTCTGTACCACTCTCATTGCTGTTATTCTAGGTATTGTGCTGGTGGTGAGCATCAAGCCTGGTGTCACCCAGAAAGTGGGTGAAATTGCGAGGACAGGCAGCACCCCTGAAGTCAGTACGGTGGATGCCATGTTAGATCTCATCAGGAATATGTTCCCTGAGAATCTTGTCCAGGCCTGTTTTCAGCAGTACAAAACTAAGCGTGAAGAAGTGAAGCCTCC

esiRNA cDNA target sequence

GATTCGTCCTTCCTGTTGGAGCAACCATTAACATGGATGGTACAGCCCTTTATGAAGCGGTAGCCGCCATCTTTATAGCCCAAATGAATGGTGTTGTCCTGGATGGAGGACAGATTGTGACTGTAAGCCTCACAGCCACCCTGGCAAGCGTCGGCGCGGCCAGTATCCCCAGTGCCGGGCTGGTCACCATGCTCCTCATTCTGACAGCCGTGGGCCTGCCAACAGAGGACATCAGCCTGCTGGTGGCTGTGGACTGGCTGCTGGACAGGATGAGAACTTCAGTCAATGTTGTGGGTGACTCTTTTGGGGCTGGGATAGTCTATCACCTCTCCAAGTCTGAGCTGGATACCATTGACTCCCAGCATCGAGTGCATGAAGATATTGAAATGACCAAGACTCAATCCATTTATGATGACATGAAGAACCACAGGGAAAGCAACTCTAATCAATGTGTCTATGCTGCACACAACTCTGTCATAGTAGATGAATGCAAGGTAACTCTGGCAGCCAA

esiRNA cDNA target sequence

TTCTCCTTTCCTGGGGAACTTCTGATGAGGATGTTACAGATGCTGGTCTTACCACTTATCATCTCCAGTCTTGTCACAGGAATGGCGGCGCTAGATAGTAAGGCATCAGGGAAGATGGGAATGCGAGCTGTAGTCTATTATATGACTACCACCATCATTGCTGTGGTGATTGGCATAATCATTGTCATCATCATCCATCCTGGGAAGGGCACAAAGGAAAACATGCACAGAGAAGGCAAAATTGTACGAGTGACAGCTGCAGATGCCTTCCTGGACTTGATCAGGAACATGTTCCCTCCAAATCTGGTAGAAGCCTGCTTTAAACAGTTTAAAACCAACTATGAGAAGAGAAGCTTTAAAGTGCCCATCCAGGCCAACGAAACGCTTGTGGGTGCTGTGATAAACAATGTGTCTGAGGCCATGGAGACTCT

esiRNA cDNA target sequence

ATCACCATCGTGGACACCTTCTTCTTCCTCTTCCTCGATAACTACGGGCTGCGGAAGCTGGAAGCTTTTTTTGGACTCCTTATAACCATTATGGCCTTGACCTTTGGCTATGAGTATGTGGTGGCGCGTCCTGAGCAGGGAGCGCTTCTTCGGGGCCTGTTCCTGCCCTCGTGCCCGGGCTGCGGCCACCCCGAGCTGCTGCAGGCGGTGGGCATTGTTGGCGCCATCATCATGCCCCACAACATCTACCTGCACTCGGCCCTGGTCAAGTCTCGAGAGATAGACCGGGCCCGCCGAGCAGACATCAGAGAAGCCAACATGTACTTCCTGATTGAGGCCACCATCGCCCTGTCCGTCTCCTTTATCATCAACCTCTTTGTCATGGCTGTCTTTGGGCAGGCCTTCTACCAGAAAACCAACCAGGC

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

Ensembl | human accession no.

ENSG00000106688

Ensembl | human accession no.

ENSG00000110436

Ensembl | human accession no.

ENSG00000079215

Ensembl | human accession no.

ENSG00000018280

NCBI accession no.

NM_004170

NCBI accession no.

NM_004171

NCBI accession no.

NM_004172

NCBI accession no.

NM_000578

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

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ZAV
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Parisa Afshari et al.
PloS one, 12(9), e0183854-e0183854 (2017-09-09)
We previously reported a 84-Kb hemi-deletion copy number variant at the SLC1A1 gene locus that reduces its expression and appeared causally linked to schizophrenia. In this report, we characterize the in vivo and in vitro consequences of reduced expression of
Silvia Piccirillo et al.
Cell death & disease, 9(7), 731-731 (2018-06-30)
In brain ischemia, reduction in oxygen and substrates affects mitochondrial respiratory chain and aerobic metabolism, culminating in ATP production impairment, ionic imbalance, and cell death. The restoration of blood flow and reoxygenation are frequently associated with exacerbation of tissue injury

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