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MilliporeSigma

EHU108041

MISSION® esiRNA

targeting human SIRT7

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$242.00

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$435.00

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

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Quality Level

100

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GGAGTGTGGACACTGCTTCAGAAAGGGAGAAGCGTTAGTGCTGCCGACCTGAGCGAGGCCGAGCCACTCACCCACATGAGCATCACCCGTCTGCATGAGCAGAAGCTGGTGCAGCATGTGGTGTCTCAGAACTGTGACGGGCTCCACCTGAGGAGTGGGCTGCCGCGCACGGCCATCTCCGAGCTCCACGGGAACATGTACATTGAAGTCTGTACCTCCTGCGTTCCCAACAGGGAGTACGTGCGGGTGTTCGATGTGACGGAGCGCACTGCCCTCCACAGACACCAGACAGGCCGGACCTGCCACAAGTGTGGGACCCAGCTGCGGGACACCATTGTGCACTTTGGGGAGAGGGGGACGTTGGGGCAGCCTTTGAACTGGGAAGCGACCGAGGCTGCCAGCAGAGCAGACACCATCCT

Ensembl | human accession no.

ENSG00000187531

NCBI accession no.

NM_016538

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... SIRT7(51547), SIRT7(51547)

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1 of 4

This Item
EHU123541EHU094501EHU149041
MISSION® esiRNA targeting human SIRT7

Sigma-Aldrich

EHU108041

MISSION® esiRNA

MISSION® esiRNA targeting human LARP7

Sigma-Aldrich

EHU123541

MISSION® esiRNA

MISSION® esiRNA targeting human RTFDC1 (1)

Sigma-Aldrich

EHU094501

MISSION® esiRNA

MISSION® esiRNA targeting human LGSN

Sigma-Aldrich

EHU149041

MISSION® esiRNA

Gene Information

human ... SIRT7(51547), SIRT7(51547)

Gene Information

human ... LARP7(51574), LARP7(51574)

Gene Information

human ... RTFDC1(51507), C20orf43(51507)

Gene Information

human ... LGSN(51557), LGSN(51557)

esiRNA cDNA target sequence

GGAGTGTGGACACTGCTTCAGAAAGGGAGAAGCGTTAGTGCTGCCGACCTGAGCGAGGCCGAGCCACTCACCCACATGAGCATCACCCGTCTGCATGAGCAGAAGCTGGTGCAGCATGTGGTGTCTCAGAACTGTGACGGGCTCCACCTGAGGAGTGGGCTGCCGCGCACGGCCATCTCCGAGCTCCACGGGAACATGTACATTGAAGTCTGTACCTCCTGCGTTCCCAACAGGGAGTACGTGCGGGTGTTCGATGTGACGGAGCGCACTGCCCTCCACAGACACCAGACAGGCCGGACCTGCCACAAGTGTGGGACCCAGCTGCGGGACACCATTGTGCACTTTGGGGAGAGGGGGACGTTGGGGCAGCCTTTGAACTGGGAAGCGACCGAGGCTGCCAGCAGAGCAGACACCATCCT

esiRNA cDNA target sequence

AAAAACCTCTGGGGGAAAGACCAAAGGATGAGGATGAACGCACAGTGTATGTGGAGTTACTTCCCAAAAATGTTAATCACAGCTGGATTGAAAGAGTATTTGGGAAATGTGGCAATGTTGTTTATATAAGTATACCACATTATAAGTCTACTGGAGATCCAAAGGGATTTGCGTTTGTGGAATTTGAAACAAAAGAACAAGCAGCAAAAGCAATTGAGTTTCTTAACAACCCACCAGAAGAAGCACCAAGAAAACCTGGCATATTTCCTAAAACAGTGAAAAATAAGCCCATTCCAGCCTTAAGAGTTGTGGAAGAGAAGAAAAAGAAAAAGAAGAAGAAAGGCCGAATGAAAAAGGAAGACAATATCCAAGCCAAAGAAGAAAACATGGACACAAGCAACACCAGCATCAGTAAAATGAAAAGATCCAGACCCACATCTGAGG

esiRNA cDNA target sequence

GAATTAGTGGCCCAATGGAACTATTGTACTCTAAGTCAGGAAATATTAAGACGACCAATAGTTGCCTGTGAACTTGGCAGACTTTATAACAAAGATGCCGTCATTGAATTTCTCTTGGACAAATCTGCAGAAAAGGCTCTTGGGAAGGCAGCATCTCACATTAAAAGCATTAAGAATGTGACAGAGCTGAAGCTTTCTGATAATCCTGCCTGGGAAGGGGATAAAGGAAACACTAAAGGTGACAAGCACGATGACCTCCAGCGGGCGCGTTTCATCTGCCCCGTTGTGGGCCTGGAGATGAACGGCCGACACAGGTTCTGCTTCCTTCGGTGCTGCGGCTGTGTGTTTTCTGAGCGAGC

esiRNA cDNA target sequence

TGGTCCAGATGAGAGCACAGACTTTTACCAAGTGGAACCTTCTGAGATCCCTTTAAAACTAGAAGATGCCCTTGTGGCACTGGAAGAAGATCAATGCCTGAGACAGGCTCTAGGAGAAACCTTTATTCGATATTTTGTTGCCATGAAGAAATATGAGTTGGAGAATGAAGAAATAGCTGCAGAGAGAAATAAATTCTTAGAGTATTTTATTTAGAATAGAGCTCACAACTACTCCTTTAGACATGTAATTGTTACTTAAAGCTAATCTACCAAAACAAAAAGACTGAACTTTTGTAATTAACAACAGCAACAATAACAAGATTACGAATGCTTTTGACTTTTTTTTTTGTCCATGGAATATTTGACAGATGAAGTAGGACTGCTGAGAAGATTCTGATAACAGAAACAAACAACAAAGTTGTGGTGA

Ensembl | human accession no.

ENSG00000187531

Ensembl | human accession no.

ENSG00000174720

Ensembl | human accession no.

ENSG00000022277

Ensembl | human accession no.

ENSG00000146166

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

NCBI accession no.

NM_016538

NCBI accession no.

NM_015454

NCBI accession no.

NM_016407

NCBI accession no.

NM_001143940

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Bin Jia et al.
IUBMB life, 73(1), 264-272 (2020-12-17)
Oral squamous cell carcinoma (OSCC) is a common malignant cancer with unfavorable prognosis, and the epithelial-to-mesenchymal transition (EMT) is a critical contributor to OSCC metastasis. Recently, we have shown that sirtuin 7 (Sirt7) is associated with EMT and OSCC metastasis
Romain Haider et al.
Oncotarget, 8(44), 77309-77316 (2017-11-05)
Predictive biomarkers for advanced prostate cancer (PCa) are still missing. The sirtuin 7 (SIRT7) has been linked to tumorogenesis but its role in prostate cancer is poorly documented. To determine if SIRT7 can be a biomarker for aggressive prostate cancer
Anne E Wyman et al.
American journal of physiology. Lung cellular and molecular physiology, 312(6), L945-L958 (2017-04-08)
Pulmonary fibrosis is a severe condition with no cure and limited therapeutic options. A better understanding of its pathophysiology is needed. Recent studies have suggested that pulmonary fibrosis may be driven by accelerated aging-related mechanisms. Sirtuins (SIRTs), particularly SIRT1, SIRT3
Wang Wei et al.
American journal of cancer research, 7(9), 1788-1803 (2017-10-06)
It is still a controversy whether the role of Sirtuin 7 (SIRT7) is an oncogene or a tumor suppressor gene in cancer as SIRT7 may have different functions in different types of cancer. Particularly, the specific roles of SIRT7 in
Yingying Zhao et al.
Oncology reports, 44(3), 959-972 (2020-07-25)
Increasing evidence has indicated the roles of sirtuin 7 (SIRT7) in numerous human cancers. However, the effects and the clinical significance of SIRT7 in human lung cancer is largely unknown. The present research demonstrated that SIRT7 was increased in human
View All Related Papers

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