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MilliporeSigma

EHU158921

Sigma-Aldrich

MISSION® esiRNA

targeting human IL1RL1

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$242.00
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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

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description

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Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GAAATCGTGTGTTTGCCTCAGGCCAACTTCTGAAGTTTCTACCAGCTGCAGTTGCTGATTCTGGTATTTATACCTGTATTGTCAGAAGTCCCACATTCAATAGGACTGGATATGCGAATGTCACCATATATAAAAAACAATCAGATTGCAATGTTCCAGATTATTTGATGTATTCAACAGTATCTGGATCAGAAAAAAATTCCAAAATTTATTGTCCTACCATTGACCTCTACAACTGGACAGCACCTCTTGAGTGGTTTAAGAATTGTCAGGCTCTTCAAGGATCAAGGTACAGGGCGCACAAGTCATTTTTGGTCATTGATAATGTGATGACTGAGGACGCAGGTGATTACACC

Ensembl | human accession no.

ENSG00000115602

NCBI accession no.

NM_016232

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... IL1RL1(9173), IL1RL1(9173)

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MISSION® esiRNA targeting human IL1RL1

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MISSION® esiRNA targeting human IDI2

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MISSION® esiRNA

MISSION® esiRNA targeting human ZW10

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EHU050301

MISSION® esiRNA

Gene Information

human ... IL1RL1(9173), IL1RL1(9173)

Gene Information

human ... CLDN8(9073), CLDN8(9073)

Gene Information

human ... IDI2(91734), IDI2(91734)

Gene Information

human ... ZW10(9183), ZW10(9183)

esiRNA cDNA target sequence

GAAATCGTGTGTTTGCCTCAGGCCAACTTCTGAAGTTTCTACCAGCTGCAGTTGCTGATTCTGGTATTTATACCTGTATTGTCAGAAGTCCCACATTCAATAGGACTGGATATGCGAATGTCACCATATATAAAAAACAATCAGATTGCAATGTTCCAGATTATTTGATGTATTCAACAGTATCTGGATCAGAAAAAAATTCCAAAATTTATTGTCCTACCATTGACCTCTACAACTGGACAGCACCTCTTGAGTGGTTTAAGAATTGTCAGGCTCTTCAAGGATCAAGGTACAGGGCGCACAAGTCATTTTTGGTCATTGATAATGTGATGACTGAGGACGCAGGTGATTACACC

esiRNA cDNA target sequence

GACTGATGTGTGCTGCTTCCGTGATGTCCTTCTTGGCTTTCATGATGGCCATCCTTGGCATGAAATGCACCAGGTGCACGGGGGACAATGAGAAGGTGAAGGCTCACATTCTGCTGACGGCTGGAATCATCTTCATCATCACGGGCATGGTGGTGCTCATCCCTGTGAGCTGGGTTGCCAATGCCATCATCAGAGATTTCTATAACTCAATAGTGAATGTTGCCCAAAAACGTGAGCTTGGAGAAGCTCTCTACTTAGGATGGACCACGGCACTGGTGCTGATTGTTGGAGGAGCTCTGTTCTGCTGCGTTTTTTGTTGCAACGAAAAGAGCAGTAGCTACAGATACTCGATACCTTCCCATCGCACAACCCAAAAAAGTTATCACACCGGAAAGAAGTCACCGAGCGTC

esiRNA cDNA target sequence

TCACAGCCAGCAGCTATGTCTGACATAAATCTTGACTGGGTTGACAGGCGTCAGTTGCAGCGCTTGGAGGAAATGCTGATTGTTGTGGATGAGAATGATAAGGTTATTGGTGCCGACACCAAGAGGAATTGCCATCTGAACGAAAACATTGAGAAAGGGCTGCTGCACCGAGCCTTCAGCGTTGTCTTGTTTAACACCAAGAATCGAATCCTGATACAGCAGAGGTCGGACACGAAAGTCACGTTTCCTGGGTATTTTACCGACTCCTGTAGTAGCCACCCATTATACAACCCAGCAGAACTGGAAGAAAAGGATGCCATCGGAGTGAGGAGGGCAGCCCAGAGGCGTCTGCAAGCAGAGCTGGGAATTCCTGGGGAGCAGATTTCTCCAGAGGACATTGTGTTCATGACAATCTATCACCACAAGGCAAAATCAGACAGAATTTGGGGAGAGCATGAA

esiRNA cDNA target sequence

GGAGACATGATCTGGGAGGACTTGTCTGAGTGCCTCATCAAAAACTGTTTGGTTTATTCGATTCCAACAAATAGCAGCAAATTACAGCAATATGAAGAGATCATACAGTCCACTGAAGAATTTGAAAATGCCCTAAAGGAAATGAGATTTTTAAAAGGAGATACTACAGATTTGCTGAAATACGCTCGTAACATCAATTCTCATTTTGCAAACAAAAAGTGCCAGGATGTGATTGTGGCAGCCAGAAATCTAATGACCTCAGAAATTCATAACACTGTGAAGATTATTCCTGATTCTAAGATAAATGTGCCAGAGTTACCCACTCCTGATGAGGATAACAAACTGGAAGTACAGAAAGTATCCAATACTCAGTACCACGAAGTGATGAATTTAGAGCCTGAAAATACATTGGACCAACATTCCTTTTCCTTGCCCACATGCCGTATCAGTGAG

Ensembl | human accession no.

ENSG00000115602

Ensembl | human accession no.

ENSG00000156284

Ensembl | human accession no.

ENSG00000148377

Ensembl | human accession no.

ENSG00000086827

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

NCBI accession no.

NM_016232

NCBI accession no.

NM_199328

NCBI accession no.

NM_033261

NCBI accession no.

NM_004724

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Xi-Xiang Yu et al.
Digestive diseases and sciences, 60(5), 1265-1272 (2015-02-07)
As a pro-inflammatory cytokine, IL-33 has been demonstrated to play an important role in tumor progression. It is reported that IL-33 is highly expressed in the serum and tumor tissues of patients with gastric cancer. However, the function of IL-33
S Stojkovic et al.
Journal of thrombosis and haemostasis : JTH, 12(6), 948-957 (2014-04-08)
Urokinase-type plasminogen activator (u-PA) plays a pivotal role in extracellular proteolysis and is thought to be critically involved in the modulation of angiogenesis. Interleukin (IL)-33 is a member of the IL-1 cytokine family, which is thought to act as danger
Anne Marie Thompson et al.
American journal of physiology. Heart and circulatory physiology, 307(4), H533-H541 (2014-06-29)
Loss of vascular smooth muscle cell (VSMC) function is a hallmark of vascular disease. VSMCs become increasingly dysregulated, apoptotic, and senescent as we age. Sirtuin 1 (SirT1) is a deactylase that regulates substrates associated with stress mitigation, metabolism, and aging.

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