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EMU002931

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Atp7b

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UNSPSC Code:
41105324
NACRES:
NA.51

description

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Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTCTTGCGTCAAGTCCATTGAGGACAGGATCTCCAGTCTGAAAGGCATTGTGAACATCAAGGTGTCCCTGGAACAAGGCAAGCACACTGTCAGATATGTGCCGTCTGTCATGAACCTGCAGCAGATTTGCCTTCAGATTGAGGATATGGGCTTTGAGGCCAGCGCTGCAGAGGGAAAGGCCGCCTCCTGGCCTTCCAGGTCCTCCCCAGCCCAGGAGGCGGTGGTCAAGCTCCGGGTAGAGGGCATGACCTGTCAGTCCTGTGTCAGCTCTATCGAGGGCAAGATCCGGAAACTGCAAGGGGTTGTGAGAATCAAAGTCTCCCTAAGCAACCAAGAGGCAGTCATTACCTATCAGCCTTACCTCATTCAACCCGAAGACCTCAGGGACCACATCTGTGACATGGG

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

flash_point_f

Not applicable

flash_point_c

Not applicable


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Xue Fu et al.
Toxicological sciences : an official journal of the Society of Toxicology, 139(2), 432-451 (2014-03-13)
Regulation of cellular copper (Cu) homeostasis involves Cu-transporting ATPases (Cu-ATPases), i.e., ATP7A and ATP7B. The question as to how these Cu-ATPases in brain barrier systems transport Cu, i.e., toward brain parenchyma, cerebrospinal fluid (CSF), or blood, remained unanswered. This study

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