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MilliporeSigma

EMU040761

MISSION® esiRNA

targeting mouse Ntrk3

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Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCCAGAGCCTTTACTGCATCAGTGCTGATGGCTCCCAACTCCCCCTCTTCCGCATGAACATCAGTCAGTGTGATCTCCCAGAGATCAGTGTGAGCCACGTCAACCTGACTGTCCGAGAAGGAGACAATGCCGTGATCACTTGCAATGGCTCTGGCTCTCCTTTGCCTGATGTGGACTGGATAGTCACTGGGCTGCAGTCCATCAACACCCACCAGACCAATCTGAACTGGACCAATGTACATGCCATCAACTTGACCCTGGTGAACGTGACGAGCGAGGACAATGGCTTCACCCTGACGTGCATTGCAGAGAACGTGGTGGGCATGAGCAATGCCAGTGTTGCTCTCACTGTCTACTACCCTCCACGTGTGGTGAGCCTGGTGGAGCCTGAGGTACGCCTGGAACATTGCATTGAGTTTGTGGTGCGTGGCAACCCGACACCCACGCTCCACTGGCTGTACAATGGACAGCCATTGAGGGAGTCCAAGATCATTCACATGGACTACTACCAGGAGGGGGAGG

Ensembl | mouse accession no.

ENSMUSG00000059146

NCBI accession no.

NM_182809

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... NTRK3(18213), Ntrk3(18213)

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esiRNA cDNA target sequence

GCCAGAGCCTTTACTGCATCAGTGCTGATGGCTCCCAACTCCCCCTCTTCCGCATGAACATCAGTCAGTGTGATCTCCCAGAGATCAGTGTGAGCCACGTCAACCTGACTGTCCGAGAAGGAGACAATGCCGTGATCACTTGCAATGGCTCTGGCTCTCCTTTGCCTGATGTGGACTGGATAGTCACTGGGCTGCAGTCCATCAACACCCACCAGACCAATCTGAACTGGACCAATGTACATGCCATCAACTTGACCCTGGTGAACGTGACGAGCGAGGACAATGGCTTCACCCTGACGTGCATTGCAGAGAACGTGGTGGGCATGAGCAATGCCAGTGTTGCTCTCACTGTCTACTACCCTCCACGTGTGGTGAGCCTGGTGGAGCCTGAGGTACGCCTGGAACATTGCATTGAGTTTGTGGTGCGTGGCAACCCGACACCCACGCTCCACTGGCTGTACAATGGACAGCCATTGAGGGAGTCCAAGATCATTCACATGGACTACTACCAGGAGGGGGAGG

esiRNA cDNA target sequence

GAGGAGCAAATTTGGGATCAACCGCCCTGCTGTATTAGCTCCAGAGGATGGGCTGGCCATGTCCCTACACTTCATGACACTGGGTGGCAGTTCTCTTTCCCCTACTGAGGGCAAAGGCTCCGGACTCCAGGGCCACATCATGGAGAACCCACAGTACTTCAGTGATACCTGTGTCCATCACATCAAGCGCCAGGACATCATTCTCAAGTGGGAGCTAGGGGAGGGAGCCTTTGGAAAGGTCTTTCTCGCTGAGTGCTACAACCTTCTGAATGATCAGGACAAGATGCTCGTGGCTGTCAAGGCACTGAAGGAGGCATCCGAGAATGCTCGGCAGGACTTTCAGCGTGAGGCCGAGCTGCTCACCATGCTACAGCACCAGCACATCGTGCGCTTCTTTGGAGTCTGCACC

esiRNA cDNA target sequence

CGGCACATAAATTTCACACGAAACAAGCTGACGAGTTTGTCCAGGAGACATTTCCGCCACCTTGACTTGTCTGACCTGATCCTGACGGGTAATCCGTTCACGTGCTCCTGCGACATCATGTGGCTCAAGACTCTCCAGGAGACTAAATCCAGCCCCGACACTCAGGATTTGTACTGCCTCAATGAGAGCAGCAAGAACATGCCCCTGGCGAACCTGCAGATACCCAATTGTGGTCTGCCATCTGCACGTCTGGCTGCTCCTAACCTCACCGTGGAGGAAGGAAAGTCTGTGACCCTTTCCTGCAGTGTGGGGGGTGACCCACTCCCCACCTTGTACTGGGACGTTGGGAATTTGGTTTCCAAGCACATGAATGAAACAAGCCACACACAGGGCTCCTTAAGGATAACGAACATTTCATCTGATGACAGTGGAAAGCAAATCTCTTGTGTGGCAGAAAACCTTGTAGGAGAAGATCAAGATTCTGTGAACCTCACTGTGCATTTTGCGCCAACTATCACGTTTCTCGAGTCTCCAACCTCAGATCACCACTGGTGCATTCCATTCACTGT

esiRNA cDNA target sequence

ATGGCTCCATCTCCATTCTGGGTTCTGATGATGCTACCACTTGTCACATTGTAGTCCTGAGACATACAGGAAATGGGGCAACCTGCCTGACACATTGTGATGGATCTGACACCAAAGCTGAAGTCCCCTTGATAATGAGCTCCATAAAATCCTTCTCTGAACATGCTGAGTGTGGAAGGCTGGAAGTACATCTTGTGGGAGGCTTCAGTGATGACAGGCAGCTGTCACAGAAACTTACTCATCAGCTTCTCAGTGAATTTGACAAACAGGATGATGACATTCACTTAGTGACATTATGTGTAACAGAGTTAAATGACCGTGAAGAAAATGAAAATCACTTTCCAATCATTTATGGCATCGCTGTCAACATTAAAACTGCAGAGATTTACAGAGCTTCCTTTCAAGATCGTGGTCC

Ensembl | mouse accession no.

ENSMUSG00000059146

Ensembl | mouse accession no.

ENSMUSG00000028072

Ensembl | mouse accession no.

ENSMUSG00000055254

Ensembl | mouse accession no.

ENSMUSG00000022681

Gene Information

mouse ... NTRK3(18213), Ntrk3(18213)

Gene Information

mouse ... NTRK1(18211), Ntrk1(18211)

Gene Information

mouse ... NTRK2(18212), Ntrk2(18212)

Gene Information

mouse ... NTAN1(18203), Ntan1(18203)

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

NCBI accession no.

NM_182809

NCBI accession no.

NM_001033124

NCBI accession no.

NM_008745

NCBI accession no.

NM_010946

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.
MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Cornelia Demel et al.
Journal of neuroinflammation, 8(1), 7-7 (2011-01-26)
Hearing loss is a frequent long-term complication of pneumococcal meningitis (PM). Its main pathological correlate is damage to the organ of Corti and loss of spiral ganglion neurons. The only current treatment option is cochlear implants which require surviving neurons.
Lei Li et al.
Cellular & molecular biology letters, 20(3), 385-403 (2015-07-26)
We investigated whether neurotrophin-3 (NT-3) can promote differentiation of mouse bone mesenchymal stem cells (MSCs) into neurons via the bone morphogenetic protein pathway. MSCs were prepared from rat bone marrow and either transfected with pIRES2-EGFP or pIRES2-EGFP-NT-3 or treated with

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