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MilliporeSigma

EMU051841

MISSION® esiRNA

targeting mouse Grem1

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About This Item

NACRES:
NA.51
UNSPSC Code:
41105324

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description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TTCTGCAAGCCCAAGAAGTTCACCACCATGATGGTCACACTCAACTGTCCTGAGCTACAGCCACCCACCAAGAAGAAAAGGGTCACACGCGTGAAGCAGTGCCGTTGCATATCCATCGACTTGGATTAAGTCAAAGCGGGCACATTCAGCCTGTCATAGCCATGCTGAGAGAGCCACACCCAAACCACCCGATTCCTACTTGGCTTAAACCTAGAGGCCAGAAGAACCAGCAGTTGCTTCCTGGCTGGAGGCTGCTTATGCATAGTGTATGCGCATGAGTGTGCATGGGTGCCTGTGGGTGTTTCCAAACACCAGCCGGAAACAGCCTTTGCTAGAAGGCACTTCCTGTTACTCTGCTTCAGATGGTCGGAAATGCCCACACCACTGGACCCAAACATCCACAGGGGCAGGGCTGTAGTTGGCTTTGTCATTGTGTTCCATGTGCCT

Ensembl | mouse accession no.

ENSMUSG00000074934

NCBI accession no.

NM_011824

shipped in

ambient

storage temp.

−20°C

Quality Level

100

Gene Information

mouse ... GREM1(23892), Grem1(23892)

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EMU026201EMU190261EMU039021
MISSION® esiRNA targeting mouse Grem1

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MISSION® esiRNA

MISSION® esiRNA targeting mouse Grem2

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EMU026201

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MISSION® esiRNA targeting mouse C1ql1

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EMU190261

MISSION® esiRNA

MISSION® esiRNA targeting mouse Grm1

Sigma-Aldrich

EMU039021

MISSION® esiRNA

Ensembl | mouse accession no.

ENSMUSG00000074934

Ensembl | mouse accession no.

ENSMUSG00000050069

Ensembl | mouse accession no.

ENSMUSG00000045532

Ensembl | mouse accession no.

ENSMUSG00000019828

product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

esiRNA cDNA target sequence

TTCTGCAAGCCCAAGAAGTTCACCACCATGATGGTCACACTCAACTGTCCTGAGCTACAGCCACCCACCAAGAAGAAAAGGGTCACACGCGTGAAGCAGTGCCGTTGCATATCCATCGACTTGGATTAAGTCAAAGCGGGCACATTCAGCCTGTCATAGCCATGCTGAGAGAGCCACACCCAAACCACCCGATTCCTACTTGGCTTAAACCTAGAGGCCAGAAGAACCAGCAGTTGCTTCCTGGCTGGAGGCTGCTTATGCATAGTGTATGCGCATGAGTGTGCATGGGTGCCTGTGGGTGTTTCCAAACACCAGCCGGAAACAGCCTTTGCTAGAAGGCACTTCCTGTTACTCTGCTTCAGATGGTCGGAAATGCCCACACCACTGGACCCAAACATCCACAGGGGCAGGGCTGTAGTTGGCTTTGTCATTGTGTTCCATGTGCCT

esiRNA cDNA target sequence

CCACCTTTCCGAATCAAGAAAATCCAGAAGGTGAAGCATTGCCGGTGCATGTCAGTGAACCTGAGTGACTCCGACAAGCAGTGAACTCATGGGGCAGGATGCAGCTCAGCCTTGAGCACTCCTACCCCTGGGTTGCGCCACCGCCACTTCTGTTGAGCTCACTCACACTCTGCCCGGTGTCCCAGTCAGCAGCAAATGTGTCTCTTAGGGCCAACAGTGTCCCTGTCACAAATGAGGACCACAAGTGAAGCTTTGTCAACTGTCCCAGATCCACCCCAGGCTACACTTGTGTCTCTAAATCCACTTTGTGGATGGGACACAGAAGATGTTGGAAAACTCCACTCCCAGAAACTCGACAAGATTTTTCAGGAGATGCACTGTCATCTGGGATTGACGACTCCACCATGTGGAAAAGCCAGTCTTTCCCTGGCCACATCCTACACTCCAGCTTGAGCC

esiRNA cDNA target sequence

CTCATGAGGGTTACGAGGTGCTCAAGTTTGACGACGTGGTCACCAACCTAGGCAACAACTACGATGCGGCCAGCGGCAAGTTTACATGCAACATTCCTGGCACCTACTTTTTCACCTACCACGTCCTCATGCGCGGCGGCGACGGCACCAGTATGTGGGCAGACCTCTGCAAGAACGGCCAGGTGCGGGCCAGTGCAATTGCCCAGGATGCAGACCAGAACTACGACTATGCCAGCAACAGCGTGATCCTGCATCTGGACGCAGGGGATGAGGTCTTCATCAAGCTGGATGGAGGCAAAGCACACGGGGGCAACAGCAACAAATACAGCACTTTCTCTGGCTTCATCATCTACTCGGATTGAGCCCCCCCCCCCGCACCCCTTTTCATCCGTGGCTCTTCATCCTTGGACTCCCCTCAGAGGCAAACAAGAATCCACTCCCCTACTCATTTTCAAATTGCCTGACCAAGGCTGCCGACCCTCCCAGGCTGAATTGTCCTTAGCCTGCGTCC

esiRNA cDNA target sequence

CATCATAGCCATCGCCTTTTCTTGCCTGGGCATCCTCGTGACGCTATTTGTCACCCTCATCTTTGTGCTGTACCGGGACACACCTGTGGTCAAATCCTCCAGTAGAGAGCTCTGCTATATCATTCTGGCTGGTATTTTCCTCGGCTACGTATGCCCTTTCACCCTCATCGCCAAACCTACTACCACATCCTGCTACCTCCAGCGCCTCCTAGTTGGCCTCTCTTCTGCCATGTGCTACTCTGCTCTTGTGACCAAAACCAATCGTATTGCACGCATCCTGGCTGGCAGCAAGAAGAAGATCTGTACCCGGAAGCCCAGGTTCATGAGCGCTTGGGCCCAAGTGATCATAGCCTCCATTCTGATTAGTGTACAGCTGACACTAGTGGTGACCTTGATCATCATGGAGCCTCCCATGCCCATTTTGTCCTACCCGAGCATCAAGGAAGTCTATCTTATCTGCAATACCAGCAACCTGGGTGTAGTGGCACCTGTGGGTTACAACGGACT

Gene Information

mouse ... GREM1(23892), Grem1(23892)

Gene Information

mouse ... GREM2(23893), Grem2(23893)

Gene Information

mouse ... C1QL1(23829), C1ql1(23829)

Gene Information

mouse ... GRM1(14816), Grm1(14816)

NCBI accession no.

NM_011824

NCBI accession no.

NM_011825

NCBI accession no.

NM_011795

NCBI accession no.

NP_001107805

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
GAV

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Nam Ji Sung et al.
International journal of molecular sciences, 21(23) (2020-12-09)
Gremlin-1 (GREM1), one of the bone morphogenetic protein (BMP) antagonists, can directly bind to BMPs. GREM1 is involved in organogenesis, tissue differentiation, and organ fibrosis. Recently, numerous studies have reported the oncogenic role of GREM1 in cancer. However, the role
Na Hui Kim et al.
Biochemical and biophysical research communications, 533(4), 1378-1384 (2020-10-25)
Gremlin-1 (GREM1), one of the antagonists of bone morphogenetic proteins (BMPs), has recently been reported to be overexpressed in a variety of cancers including breast cancer. GREM1 is involved in tumor promotion, but little is known about its role in
Julie R Graham et al.
Journal of cellular biochemistry, 115(9), 1539-1548 (2014-03-19)
Fibrosis is a chronic disease characterized by an excessive deposition of scar tissue in the affected organs. A central mediator of this process is transforming growth factor-β (TGF-β), which stimulates the production of extracellular matrix proteins such as collagens. MicroRNAs

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