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EMU072561

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Strada

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NACRES:
NA.51

description

Powered by Eupheria Biotech

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGCAAAGGGTTTGAGGACTTGATGACAGTGAATTTAGCCAGGTACAAACCAACGGGAGAGTATGTGACAGTACGAAGGATCAACCTAGAAGCTTGTTCCAATGAGATGGTGACATTCTTGCAGGGGGAGCTTCATGTCTCTAAACTCTTCAGCCATCCCAATATAGTACCGTATCGAGCCACCTTCATCGCAGATAATGAGCTGTGGGTCGTCACATCATTTATGGCGTACGGCTCTGCAAAGGATCTCATTGGCACACACTTCATGGATGGCATGAATGAACTGGCGATTGCATACATCCTGCAGGGGGTGCTAAAGGCCTTAGACTACATCCATCACATGGGCTATGTGCACAGGAGTGTCAAGGCCAGCCACATTCTGATCTCCACGGATGGGAAGGTCTACCTGTCTGGTTTACGCAGCAACCTTAGCATG

Ensembl | mouse accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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MISSION® esiRNA targeting mouse Strada

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MISSION® esiRNA targeting mouse Adpgk

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EMU089311

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product line

MISSION®

product line

MISSION®

product line

MISSION®

product line

MISSION®

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

esiRNA cDNA target sequence

AGGCAAAGGGTTTGAGGACTTGATGACAGTGAATTTAGCCAGGTACAAACCAACGGGAGAGTATGTGACAGTACGAAGGATCAACCTAGAAGCTTGTTCCAATGAGATGGTGACATTCTTGCAGGGGGAGCTTCATGTCTCTAAACTCTTCAGCCATCCCAATATAGTACCGTATCGAGCCACCTTCATCGCAGATAATGAGCTGTGGGTCGTCACATCATTTATGGCGTACGGCTCTGCAAAGGATCTCATTGGCACACACTTCATGGATGGCATGAATGAACTGGCGATTGCATACATCCTGCAGGGGGTGCTAAAGGCCTTAGACTACATCCATCACATGGGCTATGTGCACAGGAGTGTCAAGGCCAGCCACATTCTGATCTCCACGGATGGGAAGGTCTACCTGTCTGGTTTACGCAGCAACCTTAGCATG

esiRNA cDNA target sequence

CAGCTTGGGAAAGAACTTGGCCCTTCAGTGACGGAGTCCTTTGCCTGGGGGGCGAACCCGGCAGAACCAGACACTACAGGCCACATGAGATTGCTTTTGTGTTAGCTCTTGACTTGAGAACGTTCCATTTCTGAGATGGTTTTTAAGCCTGTGTGCCTTCAGATGGTTGGATAGACTTGAGGGTTGCATATTTAATCTCTGTAGTGAGTCGGAGACTGGAAACTTAATCTCGTTCTAAAAATTTTGGATTACTGGGCTGGAGGTATGGCTCAGCAGTTCGGTTTGTGTGCTGTTCTAGCCGAGGACTCCAGTTGTTCAGCTTCCCGGAACTCAGATCTGGCAGCTTAAGACCACCTGTCACTCCAGCCCCTGGAACATCCTTGCCTCCAAAGGCACCAGCACTGATTT

esiRNA cDNA target sequence

CGCATCACATTGCTTTATGGTTGGCAAGCCCGCCAGCCGCCTACTAGTGCACCATTAATTCTTGAGCCCTCTCATACCCGGGGAAGGAACCCACTGAGTTGCTAGTGTTTCGTGCTCAGTGACCCACACACACCATGGCTTCCGGGTGACATCTGGTTGCCTTGCTGCGGAAACATCCACCCACTGGGTGCATATATGCTGAATGGATGTGTGCGCTGTAGACACTGTCCTGTGAGCCAGTCTCCTCTAAGTTCATGCCAGCCTCAGTCACTTGAGATTTTAGGACGTCCCCATCTTGTCTCTGCATGCAACATGAGTGTTGTGGCTATCTGAACATGGCCTCTGTGGCACCTCTCCCCTTGTCAGAACGCAAGAAGCATCTTCCGAAGGTTACAGTAATTCAGTGTAACAATAGATTCATTTTTCCTCATTCAGTTACAAACGAAGCAAAATCTAGATGCTGGAAGCAACTGAAGG

esiRNA cDNA target sequence

AAACAGAGCCTCGGATCTCACCAGGATCCATTTCCACACGCTGGTCTACCACATTCTGGCAACTGTGGACGGACACTGGGCCAACCAGCTCGCAGCCGTAGCTGCGGGAGCTCGTGTAGCTGGGACACAAGCCTGTGCCACAGAAACCATAGACACCAACCGAGTGTCTCTAAGAGCACCTCAGGAGTTTACGACATCCCATTTGGAATCCGGTTCCAGGATTGTATTGAACCCAGATAAGCCAGTGGTGGAGTGGCACAGGGAGGGAATAACTTTCCACTTCACACCTGTGTTGGTGTGTAAAGACCCCGTTCGAACTGTAGGCCTTGGTGATGCCATTTCCGCTGAAGGCCTCTTCTATTCAGAAGCACGCCCTGATTAGACACGTTGTGTGAGGAATGAAAGTCACCCATCTTAAGAATTCCAGCAAGAACATAGCTTGGGAACTAGGCTTGTGAGTGTCAGAACAGTTCCTAGATCAAATTGGAATAGAGCCAAAGAAATCACAGCAGATTAAACTGTACAGATACATTCCAGCCTGTTGGC

Ensembl | mouse accession no.

ENSMUSG00000069631

Ensembl | mouse accession no.

ENSMUSG00000068105

Ensembl | mouse accession no.

ENSMUSG00000050052

Ensembl | mouse accession no.

ENSMUSG00000025236

NCBI accession no.

NM_028126

NCBI accession no.

NM_028075

NCBI accession no.

NM_173744

NCBI accession no.

NM_028121

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Sourav Kundu et al.
Biochimica et biophysica acta, 1843(12), 2816-2826 (2014-08-17)
Hyperglycemia (HG) reduces AMPK activation leading to impaired autophagy and matrix accumulation. Hydrogen sulfide (H2S) treatment improves HG-induced renovascular remodeling however, its mechanism remains unclear. Activation of LKB1 by the formation of heterotrimeric complex with STRAD and MO25 is known

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