F1641

Sigma-Aldrich

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

MDL number:
NACRES:
NA.46
Pricing and availability is not currently available.

biological source

goat

antibody form

affinity isolated antibody

antibody product type

secondary antibodies

clone

polyclonal

form

buffered aqueous solution

application(s)

direct immunofluorescence: 1:32

conjugate

FITC conjugate

storage temp.

2-8°C

Related Categories

General description

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ and λ myeloma proteins. The use of this product prevents background staining due to the presence of Fc receptors.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. The two heavy chains and two light chains of IgG are connected by a disulfide bond. It is a glycoprotein and mainly helps in immune defense. IgG is usually found as a monomer. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. About 70 percent of the total immunoglobulin consists of IgG. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

Immunogen

Purified human IgG

Application

Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is suitable for use in direct immunofluorescence (1:32).
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−FITC antibody has been used in immunofluorescence studies and flow cytometric crossmatch (FCXM).

Packaging

0.5 mL in glass insert
1, 2 mL in glass bottle

Physical form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Hazard Codes

Xn

Risk Statement

21/22

Safety Statement

36/37-60

RIDADR

NONH for all modes of transport

WGK Germany

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Diagnostic Value of Linear Fluorescence Along the Basement Membrane of Sweat Gland Ducts in Bullous Pemphigoid
Sinem B I, et al.
Acta Dermato-Venereologica, 97(5), 622-626 (2017)
B Niklasson et al.
Virology, 255(1), 86-93 (1999-03-02)
A previously unknown picornavirus was isolated from bank voles (Clethrionomys glareolus). Electron microscopy images and sequence data of the prototype isolate, named Ljungan virus, showed that it is a picornavirus. The amino acid sequences of predicted Ljungan virus capsid proteins...
Łucja Dziawer et al.
Nanomaterials (Basel, Switzerland), 9(4) (2019-04-21)
Highly localized radiotherapy with radionuclides is a commonly used treatment modality for patients with unresectable solid tumors. Herein, we propose a novel α-nanobrachytherapy approach for selective therapy of human epidermal growth factor receptor 2 (HER2)-positive breast cancer. This uses local...
Clinical significance of a positive flow crossmatch on the outcomes of cadaveric renal transplants
Ilham M A, et al.
Transplantation proceedings, 40(6), 1839-1843 (2008)
Işın Sinem Bağcı et al.
Acta dermato-venereologica, 97(5), 622-626 (2017-01-18)
Linear IgG deposits along the basement membrane of adnexa has been proposed to be useful in the diagnosis of bullous pemphigoid (BP), but no controlled studies have been performed. This study evaluated linear IgG fluorescence of the basement membrane of...

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