F2878

Ficoll^® PM 70

Type 70

• Synonym(s): Poly(sucrose-co-epichlorhydrin)
• CAS Number: 72146-89-5
• MDL number: MFCD00131071
• NACRES: NA.25

Properties

• type: Type 70
• Quality Level: 200
• form: powder
• mol wt: ~70,000
• solubility: H₂O: soluble 100 mg/mL, clear to slightly hazy, colorless to faintly yellow

Description

General description

Ficoll^® PM70, a high molecular weight branched polysaccharide polymer, is believed that they do not contain any ionized groups. This sucrose-polymer is formed by the copolymerization of sucrose with epichlorhydrin.

Application

Ficoll^® PM 70 has been used:

• as a macromolecule in a comparative study to evaluate its effect in vitrification solutions
• as a supplement in the vitrification solution for the vitrification procedure of oocytes
• as a component of low serum medium for human lung fibroblast cell culture to promote a crowded environment

Packaging

5, 25, 50, 250 g

Biochem/physiol Actions

Ficoll is commonly used as a macromolecular constituent of vitrification solutions. Due to their dense branching, Ficolls also serve as ideal, nearly spherical molecular crowding agents.

Ficoll^TM PM 70 is used as a macromolecular crowding agent in studies of cell volume signaling and protein refolding.It may be used in tissue engineering and macromolecular conformation research for the development, evaluation, and use of macromolecular crowding (MMC) systems and configurations. Ficoll PM-70 can also be used in vitrification research.

Other Notes

A nonionic synthetic polymer of sucrose.

Legal Information

Ficoll is a registered trademark of Cytiva

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves