F3667

Fibronectin Adhesion-promoting Peptide

Name: Fibronectin Adhesion-promoting Peptide
Brand: SIGMA
Price: 109 USD

≥95% (HPLC)

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About This Item

Empirical Formula (Hill Notation):

C₄₇H₇₄N₁₆O₁₀

CAS Number:

125720-21-0

Molecular Weight:

1023.19

NACRES:

NA.32

PubChem Substance ID:

329799700

UNSPSC Code:

12352209

MDL number:

MFCD00237001

Form:

powder

Assay:

≥95% (HPLC)

Biological source:

synthetic (organic)

Key Documents

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InChI

1S/C47H74N16O10/c1-4-25(2)37(45(72)73)61-41(68)32(14-8-20-55-47(52)53)58-38(65)26(3)57-40(67)31(13-7-19-54-46(50)51)59-42(69)34-15-9-21-62(34)44(71)35-16-10-22-63(35)43(70)33(17-18-36(49)64)60-39(66)29(48)23-27-24-56-30-12-6-5-11-28(27)30/h5-6,11-12,24-26,29,31-35,37,56H,4,7-10,13-23,48H2,1-3H3,(H2,49,64)(H,57,67)(H,58,65)(H,59,69)(H,60,66)(H,61,68)(H,72,73)(H4,50,51,54)(H4,52,53,55)/t25-,26-,29-,31-,32-,33-,34-,35-,37-/m0/s1

SMILES string

CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@@H]2CCCN2C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)Cc3c[nH]c4ccccc34)C(O)=O

InChI key

OVXIMRGEBNSORH-PJRZOMOUSA-N

biological source

synthetic (organic)

assay

≥95% (HPLC)

form

powder

composition

Peptide content, ~70%

storage temp.

−20°C

Quality Level

200

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Show Differences

1 of 4

This Item	F5007	A5686	H6894
Sigma-Aldrich F3667 Fibronectin Adhesion-promoting Peptide	Sigma-Aldrich F5007 Fibronectin Type III Connecting Segment Fragment 1-25	Sigma-Aldrich A5686 Arg-Gly-Glu-Ser acetate salt	Sigma-Aldrich H6894 [Tyr(SO₃H)⁶³]-Hirudin Fragment 54-65
assay ≥95% (HPLC)	assay ≥90% (HPLC)	assay ≥95% (HPLC)	assay ≥95% (HPLC)
biological source synthetic (organic)	biological source synthetic (organic)	biological source synthetic (organic)	biological source synthetic (organic)
form powder	form powder	form powder	form powder
storage temp. −20°C	storage temp. −20°C	storage temp. −20°C	storage temp. −20°C
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
composition Peptide content, ~70%	composition -	composition -	composition -

Other Notes

Sequence found in the carboxy-terminal heparin-binding domain of fibronectin.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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A synthetic peptide from the COOH-terminal heparin-binding domain of fibronectin promotes focal adhesion formation.

A Woods et al.

Molecular biology of the cell, 4(6), 605-613 (1993-06-01)

Cell adhesion to extracellular matrix molecules such as fibronectin involves complex transmembrane signaling processes. Attachment and spreading of primary fibroblasts can be promoted by interactions of cell surface integrins with RGD-containing fragments of fibronectin, but the further process of focal

Articles

Fibronectin

Fibronectin (FN) plays crucial roles in extracellular matrix fibril assembly and cellular interactions.

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Fibronectin Adhesion-promoting Peptide