Skip to Content
MilliporeSigma
All Photos(4)

Key Documents

F5013

Sigma-Aldrich

5-Fluoroorotic acid hydrate

≥98%

Synonym(s):

2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid, 5-Fluorouracil-4-carboxylic acid

Sign Into View Organizational & Contract Pricing

Select a Size

50 MG
$188.00
250 MG
$315.00
1 G
$945.00

$188.00


In StockDetails


Request a Bulk Order

Select a Size

Change View
50 MG
$188.00
250 MG
$315.00
1 G
$945.00

About This Item

Empirical Formula (Hill Notation):
C5H3FN2O4 · xH2O
CAS Number:
Molecular Weight:
174.09 (anhydrous basis)
EC Number:
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
NACRES:
NA.32

$188.00


In StockDetails


Request a Bulk Order

biological source

synthetic

assay

≥98%

form

powder

technique(s)

cell culture | plant: suitable

mp

278 °C (dec.) (lit.)

solubility

4 M NH4OH: 50 mg/mL, clear, colorless to light yellow

storage temp.

−20°C

SMILES string

OC(C(NC(N1)=O)=C(F)C1=O)=O.[H]O[H]

InChI

1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2

InChI key

LODRRYMGPWQCTR-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
47190F6627C9375
assay

≥98%

assay

≥99.0% (TLC)

assay

≥99% (HPLC)

assay

≥98% (TLC)

solubility

4 M NH4OH: 50 mg/mL, clear, colorless to light yellow

solubility

4 M NH4OH: 50 mg/mL, clear, faintly yellow

solubility

1 M NH4OH: soluble, DMSO/DMF: soluble, methanol: soluble

solubility

1 M NaOH: 50 mg/mL, clear, colorless to faintly yellow

technique(s)

cell culture | plant: suitable

technique(s)

-

technique(s)

titration: suitable

technique(s)

-

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

solid

form

powder

form

powder

storage temp.

−20°C

storage temp.

−20°C

storage temp.

room temp

storage temp.

-

Application

5-Fluoroorotic acid hydrate has also been used as a counter-selection agent to screen L. lactis (multi) peptidase knockout mutants[1] and C. albicans.[2] It has been used in synthesis of 5-fluoroorotidine 5′-monophosphate (FOMP).[3]
Useful in the selection of orotidine-5′-phosphate decarboxylase mutants of Saccharomyces cerevisiae.

Biochem/physiol Actions

5-Fluoroorotic acid is a selective inhibitor of rRNA synthesis in mammals.[4]

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service