G0674

SAFC

GlycylGlycine

PharmaGrade, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production

Synonym(s):
Diglycine, Glycyl-glycine, Gly-Gly
Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
Molecular Weight:
132.12
Beilstein/REAXYS Number:
1765223
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21
Pricing and availability is not currently available.

Quality Level

biological source

synthetic

Agency/Method

non-compendial

product line

PharmaGrade

form

powder

impurities

heavy metals, tested

useful pH range

7.5 - 8.9

pKa (25 °C)

8.2

suitability

suitable for manufacturing use

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

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General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Application

Glycylglycine is the dipeptide of glycine and one of the simplest peptides. It also works as a buffering agent.

Packaging

100 g in poly bottle

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Armando Tripodi et al.
European journal of internal medicine, 25(5), 449-451 (2014-05-03)
Statins are cholesterol-lowering agents with antithrombotic effect possibly unrelated to their lipid-lowering properties. Traditional global coagulation tests failed, however, to reveal clinically relevant change after treatment. We therefore sought to investigate whether statins were able to modify thrombin generation in...
Francis Impens et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(34), 12432-12437 (2014-08-13)
SUMOylation is an essential ubiquitin-like modification involved in important biological processes in eukaryotic cells. Identification of small ubiquitin-related modifier (SUMO)-conjugated residues in proteins is critical for understanding the role of SUMOylation but remains experimentally challenging. We have set up a...
Nicole C Narrandes et al.
BMC microbiology, 15, 22-22 (2015-02-06)
Molybdopterin cofactor (MoCo) biosynthesis in Mycobacterium tuberculosis is associated with a multiplicity of genes encoding several enzymes in the pathway, including the molybdopterin (MPT) synthase, a hetero tetramer comprising two MoaD and two MoaE subunits. In addition to moaD1, moaD2...
G C Cook
Gut, 17(4), 252-257 (1976-04-01)
Using a double-lumen tube jejunal perfusion system in vivo, the mutual effects of carnosine (beta-alanyl-L-histidine) and glycylglycine on their respective absorption rates have been studied in six Zambian African adults. Data on the effect of the constituent amino-acids of carnosine...
Cumali Efe et al.
European journal of gastroenterology & hepatology, 27(6), 649-654 (2015-04-11)
There are no validated noninvasive markers of liver fibrosis in autoimmune hepatitis (AIH). An activated renin-angiotensin system (RAS) and its key element angiotensin-converting enzyme (ACE) have been implicated in the pathogenesis of hepatic fibrogenesis. We aimed to study the assumed...

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