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G0885

Glycogen from bovine liver

≥85% dry basis (enzymatic)

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About This Item

Linear Formula:
(C6H10O5)n
CAS Number:
9005-79-2
UNSPSC Code:
12352201
NACRES:
NA.25
EC Number:
232-683-8
MDL number:
MFCD23701213
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biological source

bovine liver

Quality Level

200

assay

≥85% dry basis (enzymatic)

form

powder

color

white to off-white

storage temp.

2-8°C

SMILES string

O1[C@@H]([C@@H]([C@H]([C@@H]([C@H]1CO[C@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)O[C@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)O)O)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O)CO

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

Glycogen from bovine liver may be used in carbohydrate storage and metabolism research and to study various enzymes such as alpha-glucosidase(s) (GAA) and glycogen phosphorylase(s) (GPase).[1] Glycogen may be used as a substrate to identify and characterize its metabolizing enzymes.[1]

Preparation Note

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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This Item
G1508G1767361507
Sigma-Aldrich

Sigma-Aldrich

G0885

Glycogen from bovine liver

Sigma-Aldrich

Sigma-Aldrich

G1508

Glycogen from mussel, Mytilus genus

Glycogen from mussel, Mytilus genus for DNA precipitations

Sigma-Aldrich

G1767

Glycogen from mussel, Mytilus genus

Glycogen, Molecular Biology Grade, Mussel Suitable as a carrier substance for the precipitation of nucleic acids. One µl is sufficient to precipitate picogram quantities of nucleic acid with Ethanol.

Millipore

361507

Glycogen, Molecular Biology Grade, Mussel

biological source

bovine liver

biological source

(Mytilus genus)

biological source

-

biological source

-

assay

≥85% dry basis (enzymatic)

assay

≥85% anhydrous basis (enzymatic)

assay

-

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

liquid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

color

white to off-white

color

white to off-white

color

-

color

clear colorless

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
0000508441
0000508441
0000477312
0000477314
0000477311

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Articles

Pharmaceutical Research Applications of Carbohydrates and Polysaccharides

Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Istvan Katona et al.
Orphanet journal of rare diseases, 9, 17-17 (2014-02-06)
Glycogenosis type II or Pompe disease is an autosomal-recessive lysosomal storage disease due to mutations in the gene encoding acid alpha-glucosidase (GAA), an enzyme required for lysosomal glycogen degradation. The disease predominantly affects the skeletal and respiratory muscles but there
Louise Knudsen et al.
PloS one, 7(12), e51972-e51972 (2013-01-10)
Insulin can trigger metabolic as well as mitogenic effects, the latter being pharmaceutically undesirable. An understanding of the structure/function relationships between insulin receptor (IR) binding and mitogenic/metabolic signalling would greatly facilitate the preclinical development of new insulin analogues. The occurrence
Maria Kylä-Puhju et al.
Meat science, 69(1), 143-149 (2005-01-01)
The activity of glycogen debranching enzyme (GDE) was studied in relation to pH value and temperature in porcine masseter and longissimus dorsi muscles. A glycogen limit dextrin was used as the substrate for GDE, and the enzyme was derived from
View All Related Papers

Global Trade Item Number

SKUGTIN
G0885-25G04061835366743
G0885-5G04061833624449
G0885-1G04061833624432
G0885-10G04061833624425

Questions

1–6 of 6 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. What is the specific rotation of Product G0885, Glycogen from Bovine Liver?

    1 answer

    1. The specific rotation of this product is +196° to +197°.

      Helpful?

  4. What are glycogens?

    1 answer

    1. Per Biochemistry, Lehninger ed., 2nd ed, p. 266: A general description of glycogens is: A polymer of alpha (1->4) linked D-Glucose with alpha (1->6) branching at about ever 8 to 12 glucose residues. The molecular weight for bovine source is not mentioned, but glycogen in general is 270,000-3.5 million.

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  5. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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  6. What is the solubility of Product G0885, Glycogen from Bovine Liver?

    1 answer

    1. Sigma routinely tests the solubility in water at 50 mg/mL, yielding a hazy solution. In general, glycogens are soluble in water with opalescence and insoluble in alcohol.

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