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G1002

Sigma-Aldrich

Gly-Gly

≥99% (titration)

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Synonym(s):
Diglycine, Glycyl-glycine
Linear Formula:
NH2CH2CONHCH2COOH
CAS Number:
Molecular Weight:
132.12
Beilstein/REAXYS Number:
1765223
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥99% (titration)

form

powder

color

white

useful pH range

7.5-8.9

pKa (25 °C)

8.2

mp

262-264 °C

application(s)

diagnostic assay manufacturing

SMILES string

NCC(=O)NCC(O)=O

InChI

1S/C4H8N2O3/c5-1-3(7)6-2-4(8)9/h1-2,5H2,(H,6,7)(H,8,9)

InChI key

YMAWOPBAYDPSLA-UHFFFAOYSA-N

Gene Information

human ... SLC15A1(6564)

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1 of 4

This Item
5019950200G0674
vibrant-m

G1002

Gly-Gly

-
vibrant-m

50199

Gly-Gly

Premium Grade
vibrant-m

50200

Gly-Gly

Premium Grade
vibrant-m

G0674

GlycylGlycine

-
assay

≥99% (titration)

assay

≥99.5% (NT)

assay

≥99.0% (NT)

assay

-

Quality Level

400

Quality Level

200

Quality Level

200

Quality Level

500

color

white

color

white

color

white

color

-

mp

262-264 °C

mp

220-240 °C

mp

220-240 °C (dec.)

mp

-

useful pH range

7.5-8.9

useful pH range

7.5-8.9

useful pH range

7.5-8.9

useful pH range

7.5-8.9

Application

Gly-Gly has been used as a buffer for the measurement of glucose-6-phosphate dehydrogenase (G6PDH) activity and as a component of luciferase assay buffer.

Biochem/physiol Actions

Gly-Gly or diglycine is the simplest dipeptide. It may possess proteolytic properties. Gly-gly is hydrolyzed by glycylglycine dipeptidase.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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THE GLYCYLGLYCINE DIPEPTIDASES OF SKELETAL
MUSCLE AND HUMAN UTERUS*
EMIL L. SMITH
The Journal of Biological Chemistry (1947)
Primary Epithelial Cell Models for Cystic Fibrosis Research
Scott H. Randell
Methods in Molecular Biology null
Open questions in origin of life: experimental studies on the origin of nucleic acids and proteins with specific and functional sequences by a chemical synthetic biology approach
Katarzyna A
Computational and structural biotechnology journal, 9, e201402004-e201402004 (2014)
Zheng Ma et al.
Antimicrobial agents and chemotherapy, 53(7), 2857-2864 (2009-04-22)
Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption of colistin by the kidney in vivo, but there is no knowledge of its disposition within
P B Armentrout et al.
Journal of the American Society for Mass Spectrometry, 23(4), 621-631 (2011-09-29)
We present a full computational description of the fragmentation reactions of protonated diglycine (H(+)GG). Relaxed potential energy surface scans performed at B3LYP/6-31 G(d) or B3LYP/6-311 + G(d,p) levels are used to map the reaction coordinate surfaces and identify the transition states (TSs) and

Protocols

To measure glucose-6-phosphate dehydrogenase activity, beta-nicotinamide adenine dinucleotide phosphate is used in a spectrophotometric rate determination assay at 340 nm.

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