G1765

Sigma-Aldrich

Glycogen from oyster

Type XI

CAS Number:
EC Number:
MDL number:

biological source

animal (oyster)

type

Type XI

form

powder

application(s)

cell analysis: suitable

storage temp.

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

Oyster glycogen has been used to induce inflammation and to promote extravasation of granulocytes and neutrophils in animal models after intraperitoneal injection. Glycogen also acts as a vascular permeability probe.

Other Notes

High molecular weight

Preparation Note

Prepared by a modification of Bueding, E., and Orrell, S.A., Jr., J. Biol. Chem., 236, 2854 (1961).

Certificate of Analysis

Certificate of Origin

Juan M Pascual et al.
JAMA neurology, 70(6), 756-763 (2013-04-24)
The physiological relevance of acid maltase (acid α-glucosidase, an enzyme that degrades lysosomal glycogen) is well recognized in liver and muscle. In late (adult)-onset acid maltase deficiency (glycogen storage disease type II [GSD II]), glycogen accumulates inside muscular lysosomes in...
Hyo-Jin Jeong et al.
Biochemical and biophysical research communications, 434(3), 503-508 (2013-04-16)
MicroRNA (miRNA) is a class of endogenous small noncoding RNA that negatively regulates gene expression at the post-transcriptional level and plays an important role in the pathogenesis of various diseases. However, the identity and role of miRNAs involved in the...
Jacob Lorenzo-Morales et al.
Eukaryotic cell, 7(3), 509-517 (2008-01-29)
Acanthamoeba infections are difficult to treat due to often late diagnosis and the lack of effective and specific therapeutic agents. The most important reason for unsuccessful therapy seems to be the existence of a double-wall cyst stage that is highly...
Rui Zhu et al.
Environmental technology, 34(1-4), 429-435 (2013-03-28)
Sludge retention time (SRT) and phosphorus to carbon ratio (P/C) in the feed are important control parameters in biological phosphorus removal. In this study, humus soil sequencing batch reactor (HS-SBR) process was operated with different SRTs (five, 10 and 15...
Han Peng et al.
Investigative ophthalmology & visual science, 54(4), 2781-2786 (2013-04-04)
Corneal epithelial cells have large stores of glycogen, which serve as their primary energy source. Recently, we demonstrated that factor-inhibiting hypoxia-inducible factor 1 (FIH-1) diminished glycogen stores in vitro and in vivo, working through the Akt/Glycogen Synthase Kinase (GSK)-3β pathway....

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