G211130
DMT-2′O-Methyl-rG(ib) Phosphoramidite
configured for ABI
Synonym(s):
DMT-2′-O-Me-rG(ib) amidite, N-(2-methyl-1-oxopropyl)-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-methyl-guanosine, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Select a Size
| Size/SKU | Availability | Price |
|---|---|---|
1 g | Check Cart for Availability | $93.10 |
About This Item
biological source
non-animal source (no BSE/TSE risk)
Quality Segment
product line
Proligo Reagents
assay
≥99% (31P-NMR), ≥99.0% (reversed phase HPLC)
form
powder
technique(s)
oligo synthesis: suitable
impurities
≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content
color
white to off-white
λ
conforms (UV/VIS Identity)
suitability
conforms to structure for H-NMR, conforms to structure for LC-MS
compatibility
configured for ABI
nucleoside profile
base: guanosine
base protecting group: isobutyryl
2' protecting group: methyl
5' protecting group: DMT
deprotection: standard
storage temp.
-10 to -25°C
SMILES string
CO[C@@H]1[C@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@@H](COC(c2ccccc2)(c3ccc(OC)cc3)c4ccc(OC)cc4)O[C@H]1n5cnc6C(=O)NC(NC(=O)C(C)C)=Nc56
InChI
1S/C45H56N7O9P/c1-28(2)41(53)49-44-48-40-37(42(54)50-44)47-27-51(40)43-39(57-9)38(61-62(59-25-13-24-46)52(29(3)4)30(5)6)36(60-43)26-58-45(31-14-11-10-12-15-31,32-16-20-34(55-7)21-17-32)33-18-22-35(56-8)23-19-33/h10-12,14-23,27-30,36,38-39,43H,13,25-26H2,1-9H3,(H2,48,49,50,53,54)/t36-,38-,39-,43-,62?/m1/s1
InChI key
IRRDHRZUOZNWDJ-MLLDKZSOSA-N
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This Item | |||
|---|---|---|---|
| description configured for ABI | description - | description configured for (ÄKTA® and OligoPilot®) | description configured for MerMade |
| biological source non-animal source (no BSE/TSE risk) | biological source non-animal source (no BSE/TSE risk) | biological source non-animal source (no BSE/TSE risk) | biological source non-animal source (no BSE/TSE risk) |
| Quality Level 300 | Quality Level 300 | Quality Level 300 | Quality Level 300 |
| assay ≥99% (31P-NMR), ≥99.0% (reversed phase HPLC) | assay ≥99% (31P-NMR), ≥99.0% (reversed phase HPLC) | assay ≥99% (31P-NMR), ≥99.0% (reversed phase HPLC) | assay ≥99% (31P-NMR), ≥99.0% (reversed phase HPLC) |
| storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| color white to off-white | color white to off-white | color white to off-white | color white to off-white |
| impurities ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤3% residual Solvent content, ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤0.3% water content (Karl Fischer) | impurities ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3 wt. % water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3 wt. % residual Solvent content | impurities ≤0.1% single unspecified Impurity (reversed phase HPLC), ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content | impurities ≤0.3% mG2 (reversed phase HPLC, Hydrolysate), ≤0.3% mG3 (reversed phase HPLC, DMT-rG(ib)me), ≤0.3% water content (Karl Fischer), ≤0.5% P(III) Impurities 100-169ppm (31P-NMR), ≤0.5% single Impurity (redox titration), ≤1.0% mG1 (reversed phase HPLC, DMT-rG(ib)me-DMT), ≤3% residual Solvent content |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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