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G2878

Sigma-Aldrich

Glycocholic acid hydrate

synthetic, ≥97% (HPLC)

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Synonym(s):
3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide, Cholylglycine, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)-glycine
Empirical Formula (Hill Notation):
C26H43NO6 · xH2O
CAS Number:
Molecular Weight:
465.62 (anhydrous basis)
Beilstein/REAXYS Number:
2955826
MDL number:
PubChem Substance ID:
NACRES:
NA.25

biological source

synthetic

description

anionic

assay

≥97% (HPLC)

form

powder

mol wt

average mol wt 1000

aggregation number

2.1

technique(s)

enzyme immunoassay: suitable

CMC

7.1

functional group

amide

shipped in

ambient

storage temp.

room temp

SMILES string

O.C[C@H](CCC(=O)NCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C26H43NO6.H2O/c1-14(4-7-22(31)27-13-23(32)33)17-5-6-18-24-19(12-21(30)26(17,18)3)25(2)9-8-16(28)10-15(25)11-20(24)29;/h14-21,24,28-30H,4-13H2,1-3H3,(H,27,31)(H,32,33);1H2/t14-,15+,16-,17-,18+,19+,20-,21+,24+,25+,26-;/m1./s1

InChI key

WDKPRHOCWKLQPK-ZUHYDKSRSA-N

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This Item
739707T9034T4009
vibrant-m

G2878

Glycocholic acid hydrate

-
vibrant-m

739707

Glycodeoxycholic-2,2,4,4-d4 acid

-
vibrant-m

T9034

Taurocholic acid sodium salt hydrate

Premium Grade
vibrant-m

T4009

Taurocholic acid sodium salt hydrate

-
aggregation number

2.1

aggregation number

-

aggregation number

4

aggregation number

4

assay

≥97% (HPLC)

assay

≥98% (CP)

assay

≥95% (HPLC)

assay

≥95% (HPLC)

technique(s)

enzyme immunoassay: suitable

technique(s)

mass spectrometry (MS): suitable

technique(s)

-

technique(s)

-

storage temp.

room temp

storage temp.

−20°C

storage temp.

room temp

storage temp.

room temp

biological source

synthetic

biological source

-

biological source

synthetic (organic)

biological source

synthetic (organic)

Application

Glycocholic acid hydrate has been used in a study to assess the invasiveness of Cryptosporidium spp. Into cultured cells. It has also been used in a study to investigate the interaction of chitosan and oil-in-water emulsions under conditions simulating the digestive system.

Biochem/physiol Actions

Bile Acid

related product

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

ppe

Eyeshields, Gloves


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Protocols

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

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