Skip to Content
MilliporeSigma
All Photos(4)

Documents

G4750

Sigma-Aldrich

D-(+)-Gluconic acid δ-lactone

≥99.0% (GC)

Sign Into View Organizational & Contract Pricing

Synonym(s):
Glucono delta-lactone, δ-Gluconolactone, 1,2,3,4,5-Pentahydroxycaproic acid δ-lactone, D-(+)-Dextronic acid δ-lactone
Empirical Formula (Hill Notation):
C6H10O6
CAS Number:
Molecular Weight:
178.14
Beilstein/REAXYS Number:
83286
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

biological source

microbial

Quality Level

assay

≥99.0% (GC)

form

powder

technique(s)

gas chromatography (GC): suitable

color

white to off-white

mp

160 °C (dec.) (lit.)

solubility

water: soluble

storage temp.

room temp

SMILES string

OC[C@H]1OC(=O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H10O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-5,7-10H,1H2/t2-,3-,4+,5-/m1/s1

InChI key

PHOQVHQSTUBQQK-SQOUGZDYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

D-(+)-Gluconic acid δ-lactone (GDL) is soluble in water and hydrolyzes into gluconic acid spontaneously and homogeneously lowers the pH. Quinoprotein glucose dehydrogenase converts D-glucose to GDL which gradually lowers the pH and transcriptionally controls the prodigiosin production. GDL is commonly used in the food industry to cause gelation of sodium caseinate by acidification. GDL helps to overcome the difficulties and variations of using starter bacterial cultures.

Application

D-(+)-Gluconic acid δ-lactone has been used in the preparation of cold set gels, and hydrogels.

Biochem/physiol Actions

Glucono-d-lactone increased the doubling time and activated enzymes involved in the oxidative pentose phosphate pathway of Saccharomyces cerevisiae.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Stephanie A Fernandez et al.
Frontiers in bioengineering and biotechnology, 9, 674125-674125 (2021-06-15)
Transplantation of hydrogel-encapsulated pancreatic islets is a promising long-term treatment for type 1 diabetes that restores blood glucose regulation while providing graft immunoprotection. Most human-scale islet encapsulation devices that rely solely on diffusion fail to provide sufficient surface area to
Microencapsulation of probiotic bacteria using pH-induced gelation of sodium caseinate and gellan gum
Nag A, et al.
International dairy journal, 21(4), 247-253 (2011)
Phenotypic Basis for Matrix Stiffness-Dependent Chemoresistance of Breast Cancer Cells to Doxorubicin
Joyce MH, et al.
Frontiers in Oncology, 8, 337-337 (2018)
Enzymatic hydrolysis as a means of expanding the cold gelation conditions of soy proteins
Kuipers BJH, et al.
Journal of Agricultural and Food Chemistry, 53(4), 1031-1038 (2005)
The effect of the glucono-delta-lactone/caseinate ratio on sodium caseinate gelation
Braga ALM, et al.
International dairy journal, 16(5), 389-398 (2006)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service