G5013

G 418 disulfate salt

Name: G 418 disulfate salt
Brand: SIGMA

potency: ≥720 μg per mg (dried basis)

Synonym(s):

Antibiotic G418

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About This Item

Empirical Formula (Hill Notation):

C₂₀H₄₀N₄O₁₀ · 2H₂SO₄

CAS Number:

108321-42-2

Molecular Weight:

692.71

MDL number:

MFCD00058314

UNSPSC Code:

51102829

PubChem Substance ID:

24895193

NACRES:

NA.85

Key Documents

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Product Name

G 418 disulfate salt, potency: ≥720 μg per mg (dried basis)

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](OC[C@@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H]([C@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O

InChI

1S/C20H40N4O10.2H2O4S/c1-6(25)14-11(27)10(26)9(23)18(32-14)33-15-7(21)4-8(22)16(12(15)28)34-19-13(29)17(24-3)20(2,30)5-31-19;2*1-5(2,3)4/h6-19,24-30H,4-5,21-23H2,1-3H3;2*(H2,1,2,3,4)/t6?,7-,8+,9+,10+,11-,12-,13-,14+,15+,16-,17-,18+,19-,20+;;/m0../s1

InChI key

UHEPSJJJMTWUCP-NKCAIAFTSA-N

form

powder

potency

≥720 μg per mg (dried basis)

color

white to off-white

solubility

H₂O: 100 mg/mL

antibiotic activity spectrum

Gram-negative bacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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Show Differences

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This Item	G8168	A1720	G418-RO
Sigma-Aldrich G5013 G 418 disulfate salt	Sigma-Aldrich G8168 G 418 disulfate salt solution	Sigma-Aldrich A1720 G 418 disulfate salt	Roche G418-RO G-418 Solution
antibiotic activity spectrum Gram-negative bacteria	antibiotic activity spectrum parasites	antibiotic activity spectrum Gram-negative bacteria	antibiotic activity spectrum protozoa
mode of action protein synthesis \| interferes	mode of action protein synthesis \| interferes	mode of action protein synthesis \| interferes	mode of action protein synthesis \| inhibits
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 100
form powder	form solution	form powder	form solution
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
solubility H₂O: 100 mg/mL	solubility H₂O: 50 mg/mL, clear	solubility H₂O: 100 mg/mL (As a stock solution. Stock solutions should be stored at 2-8°C. Stable at 37°C for 8 days.)	solubility -

Disclaimer

The product is stable for three years when stored at 2-8°C. Aqueous solutions stored frozen at -20 to -70 °C should be stable for approximately six months.

General description

Chemical structure: aminoglycoside

Preparation Note

G418 powder is soluble in water at 100 mg/mL.

pictograms

GHS08

signalword

Danger

hcodes

H317,H334

pcodes

P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313

Hazard Classifications

Resp. Sens. 1 - Skin Sens. 1

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

Eyeshields, Gloves, type N95 (US)

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