The minimum purity of this material is 98% by GC. This information is reported on an 'as is' basis in the lot-specific Certificate of Analysis. Please see the link below to review a sample or lot-specific Certificate:
https://www.sigmaaldrich.com/product/sigma/g5269#product-documentation
G5269
D-Glucuronic acid
≥98% (GC)
Synonym(s):
Glucosiduronic acid
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 10 mg | Check Cart for Availability | $38.50 | |
| 10 g | Check Cart for Availability | $139.00 | |
| 25 g | Check Cart for Availability | $245.00 | |
| 50 g | Check Cart for Availability | $465.00 | |
| 100 g | Check Cart for Availability | $832.00 |
About This Item
Empirical Formula (Hill Notation):
C6H10O7
CAS Number:
Molecular Weight:
194.14
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
EC Number:
229-486-4
Beilstein/REAXYS Number:
1727083
MDL number:
$38.50
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biological source
synthetic (organic)
assay
≥98% (GC)
form
powder
optical activity
[α]/D 35 to 37°, c = 6% (w/v) in H2O (equilibrium value)
technique(s)
gas chromatography (GC): suitable
color
white to off-white
mp
159-161 °C (lit.)
solubility
H2O: soluble 100 mg/mL, clear to slightly hazy
storage temp.
room temp
SMILES string
O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O
InChI
1S/C6H10O7/c7-1-2(8)4(5(10)11)13-6(12)3(1)9/h1-4,6-9,12H,(H,10,11)/t1-,2-,3+,4-,6+/m0/s1
InChI key
AEMOLEFTQBMNLQ-QIUUJYRFSA-N
General description
Glucuronic acid is one of the component of xylan backbone, a hemicellulose present in plant cell wall.
Application
D-Glucuronic acid has been used:
- in in vitro human digestion model
- as a fibrous cellulose powder, to test the feeding preference among experimental termites
- as a standard to quantify glucuronic acid in urine sample
Biochem/physiol Actions
In humans, glucuronic acid conjugation with steroidal compounds and drugs is an important step in phase II metabolic reactions. This influences the biotransformation process of the compound.
Other Notes
To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.
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This Item | |||
|---|---|---|---|
| assay ≥98% (GC) | assay - | assay - | assay ≥99% |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| technique(s) gas chromatography (GC): suitable | technique(s) - | technique(s) - | technique(s) - |
| Quality Level 200 | Quality Level 300 | Quality Level - | Quality Level 200 |
| solubility H2O: soluble 100 mg/mL, clear to slightly hazy | solubility - | solubility - | solubility water: soluble 25 mg/mL, clear, colorless |
| form powder | form powder | form - | form powder |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Articles
Drug conjugate analysis and the enzymatic hydrolysis of glucuronides
Related Content
J R Alonso-Fernandez et al.
Journal of clinical laboratory analysis, 24(2), 106-112 (2010-03-25)
We describe the history and current implementation of an inexpensive thin layer chromatography (TLC) method, vertical sandwich-type continuous/evaporative TLC with fixed mobile phase volume, that is convenient for detecting and identifying reducing sugars of clinical relevance in the paper-borne blood
P Doig et al.
Infection and immunity, 55(6), 1517-1522 (1987-06-01)
The alginate produced by Pseudomonas aeruginosa has been reported to play a role in the adhesion of this bacterium to epithelial cell surfaces, although some controversy concerning this role exists. To clarify this controversy, we investigated the ability of alginate
Plant secondary metabolites compromise the energy budgets of specialist and generalist mammalian herbivores
Sorensen JS, et al.
Ecology, 86(1), 125-139 (2005)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| G5269-25G | 04061835366842 |
| G5269-10G | 04061835366835 |
| G5269-10MG | 04061833633960 |
| G5269-100G | 04061835366828 |
| G5269-50G | 04061835366859 |
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Is the purity of the standard ASIS standard or ANHYDROUS standard?
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is glucuronic acid hygroscopic?
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Generally, D-Glucuronic acid is hygroscopic. However, specific information confirming the hygroscopic nature of this product is not available.
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How can I determine the shelf life / expiration / retest date of this product?
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If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdfHelpful?
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Request you to share GC based Method of Analysis for the estimation of D-Glucuronic acid.
1 answer-
The purity of this product is analyzed by capillary GC with flame ionization detection (FID), and the Glucuronic Acid is run as the trimethylsilyl (TMS) derivative. The purity reported on the certificate of analysis is simply the integrated area of the largest peak. Unfortunately, the other details of the Gas Chromatography method (type of column, temperature gradient, etc.) are held as proprietary information.
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How is shipping temperature determined? And how is it related to the product storage temperature?
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Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
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