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G5502

Guaiacol

oxidation indicator

Synonym(s):

2-Methoxyphenol, Catechol monomethyl ether, Pyrocatechol monomethyl ether

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Pack SizeSKUAvailabilityPrice
100 g

Estimated to ship onJune 11, 2026fromMILWAUKEE

$70.10
250 g

Estimated to ship onJune 11, 2026fromMILWAUKEE

$99.00
500 g

Available to ship TODAYfromMILWAUKEE

$194.00
1 kg

Estimated to ship onJune 11, 2026fromMILWAUKEE

$314.00

About This Item

Linear Formula:
(CH3O)C6H4OH
CAS Number:
Molecular Weight:
124.14
UNSPSC Code:
12352202
NACRES:
NA.77
PubChem Substance ID:
EC Number:
201-964-7
Beilstein/REAXYS Number:
508112
MDL number:

$70.10


Estimated to ship onJune 11, 2026Details


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vapor density

4.27 (vs air)

Quality Level

vapor pressure

0.11 mmHg ( 25 °C)

assay

≥98.0%

form

liquid, solid

refractive index

n20/D 1.543 (lit.)

bp

205 °C (lit.)

mp

26-29 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

SMILES string

COc1ccccc1O

InChI

1S/C7H8O2/c1-9-7-5-3-2-4-6(7)8/h2-5,8H,1H3

InChI key

LHGVFZTZFXWLCP-UHFFFAOYSA-N

General description

Guaiacol, a phenolic compound, acts as a scavenger of superoxide radicals. It is produced from guaiacum or wood creosote. Guaiacol acts as a precursor to different favoring agents like, vanillin and roasted coffee. It is used as an antiseptic, analgesic and sedative drug for the treatment of dental pulp and periodontal tissue. Guaiacol enhances cell proliferation in vivo.

Application

Guaiacol has been used:
  • as a substrate for peroxidase enzyme to determine its activity
  • as a substrate to determine laccase activity
  • as a reagent in peroxidase (POD) activity test

Biochem/physiol Actions

Guaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.
Guaiacol has an ability to inhibit prostaglandin biosynthesis, without causing damage to the gastrointestinal system, unlike classic NSAID (nonsteroidal anti-inflammatory drugs).

Disclaimer

May be liquid at room temperature.

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This Item
W253200130000412-1620
assay

≥98.0%

assay

≥99%

assay

-

assay

≥98.0%

bp

205 °C (lit.)

bp

205 °C (lit.)

bp

205 °C (lit.)

bp

205 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

density

1.129 g/mL at 25 °C (lit.)

mp

26-29 °C (lit.)

mp

26-29 °C (lit.)

mp

26-29 °C (lit.)

mp

26-29 °C (lit.)

refractive index

n20/D 1.543 (lit.)

refractive index

n20/D 1.543 (lit.)

refractive index

n20/D 1.543 (lit.)

refractive index

n20/D 1.543 (lit.)

vapor density

4.27 (vs air)

vapor density

4.27 (vs air)

vapor density

4.27 (vs air)

vapor density

4.27 (vs air)


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pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

194.0 °F - closed cup

flash_point_c

90 °C - closed cup

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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Global Trade Item Number

SKUGTIN
G5502-500G04061833635292
G5502-1KG04061833635278
G5502-250G04061835326860
G5502-100G04061835326853

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Does this material can be used for analytical testing as standard ?

    1 answer
    1. This product is not tested for use as an analytical standard. Please see the link below to review product PHR1136. a pharmaceutical secondary reference standard:
      https://www.sigmaaldrich.com/product/sial/phr1136

      Helpful?

  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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