G5923

Sigma-Aldrich

8-Gingerol

Synonym(s):
8-Gingerol, (S)-5-Hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-dodecanone
Empirical Formula (Hill Notation):
C19H30O4
CAS Number:
Molecular Weight:
322.44
Beilstein/REAXYS Number:
2059802
MDL number:
PubChem Substance ID:
NACRES:
NA.25
Pricing and availability is not currently available.

color

white to yellow

storage temp.

2-8°C

SMILES string

CCCCCCCC@H(O)CC(=O)CCc1ccc(O)c(OC)c1

InChI

1S/C19H30O4/c1-3-4-5-6-7-8-16(20)14-17(21)11-9-15-10-12-18(22)19(13-15)23-2/h10,12-13,16,20,22H,3-9,11,14H2,1-2H3/t16-/m0/s1

InChI key

BCIWKKMTBRYQJU-INIZCTEOSA-N

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Packaging

5, 10 mg in glass bottle

Biochem/physiol Actions

8-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with anti-inflammatory and antioxidant activity.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Hazard Codes

Xi

Risk Statement

43

Safety Statement

36/37

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Andreas Nievergelt et al.
Bioorganic & medicinal chemistry, 18(9), 3345-3351 (2010-04-07)
Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma...
Zhufeng Wu et al.
The Journal of pharmacy and pharmacology, 67(4), 583-596 (2014-12-17)
To determine the reaction kinetics for regioselective glucuronidation of gingerols (i.e. 6-, 8- and 10-gingerol) by human liver microsomes and expressed UDP-glucuronosyltransferase (UGT) enzymes, and to identify the main UGT enzymes involved in regioselective glucuronidation of gingerols. The rates of...
Wen Xu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 986-987, 69-84 (2015-02-25)
Gua-Lou-Gui-Zhi decoction (GLGZD) is a classical formula of traditional Chinese medicine, which has been commonly used to treat dysfunction after stroke, epilepsy and spinal cord injury. In this study, a systematic method was established for chemical profiling and quantification analysis...

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