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G6392

L-Glutamine

γ-irradiated, BioXtra, suitable for cell culture

All Photos(1)

Synonym(s):

(S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

Linear Formula:

H₂NCOCH₂CH₂CH(NH₂)CO₂H

CAS Number:

56-85-9

Molecular Weight:

146.14

Beilstein:

1723797

EC Number:

200-292-1

MDL number:

MFCD00008044

eCl@ss:

32160406

PubChem Substance ID:

24895254

NACRES:

NA.75

Quality Level

200

sterility

γ-irradiated

product line

BioXtra

form

powder

packaging

vial of 0.292 g

technique(s)

cell culture | mammalian: suitable

impurities

endotoxin, tested

color

white to faint yellow

mp

185 °C (dec.) (lit.)

solubility

H₂O: 10 mL/vial, clear to slightly hazy

SMILES string

N[C@@H](CCC(N)=O)C(O)=O

InChI

1S/C5H10N2O3/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H2,7,8)(H,9,10)/t3-/m0/s1

InChI key

ZDXPYRJPNDTMRX-VKHMYHEASA-N

Gene Information

rat ... Ggt1(116568)

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Related Categories

Amino Acids

Application

L-Glutamine has been used as a media supplement:

for cochlear organotypic culturing
in Iscove′s modified Dulbecco′s medium for HeLa cells culturing
in Dulbecco′s modified Eagle′s medium for primary hepatocyte cell culturing

Biochem/physiol Actions

Glutamine mediates protein turnover via cellular mTOR (mammalian target of rapamycin) signalling. It is also known to be associated with the inhibition of apoptosis.

L-glutamine is an essential amino acid that is a crucial component of culture media, and serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

Packaging

50 mL amber serum vial with rubber stopper.

Suitability

Qualified for use in cell culture applications, especially serum-free cell culture.

Reconstitution

Prepares a 200 mM solution when reconstituted to 10 mL with sterile water.

Other Notes

The dipeptide L-Ala-LGln is frequently used in modern serum-free media formulations because it provides a more stable form of glutamine in vitro.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)