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  • G6752
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G6752

Sigma-Aldrich

Guanosine

≥98%

Synonym(s):
9-(β-D-Ribofuranosyl)guanine, Guanine-9-β-D-ribofuranoside
Empirical Formula (Hill Notation):
C10H13N5O5
CAS Number:
Molecular Weight:
283.24
Beilstein:
625911
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.51

biological source

microbial

Quality Level

Assay

≥98%

form

powder

mp

250 °C (dec.) (lit.)

solubility

formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

SMILES string

[H]O[H].NC1=Nc2c(ncn2[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C(=O)N1

InChI

1S/C10H13N5O5/c11-10-13-7-4(8(19)14-10)12-2-15(7)9-6(18)5(17)3(1-16)20-9/h2-3,5-6,9,16-18H,1H2,(H3,11,13,14,19)/t3-,5-,6-,9-/m1/s1

InChI key

NYHBQMYGNKIUIF-UUOKFMHZSA-N

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This Item
G119507590351030
Guanosine ≥98%

Sigma-Aldrich

G6752

Guanosine

Guanine 98%

Sigma-Aldrich

G11950

Guanine

Guanosine ≥97.0% (HPLC)

Sigma-Aldrich

75903

Guanosine

Guanine hydrochloride ≥99.0%

Sigma-Aldrich

51030

Guanine hydrochloride

biological source

microbial

biological source

-

biological source

-

biological source

-

assay

≥98%

assay

98%

assay

≥97.0% (HPLC)

assay

≥99.0%

form

powder

form

-

form

powder

form

powder

mp

250 °C (dec.) (lit.)

mp

>300 °C (lit.)

mp

250 °C (dec.) (lit.)

mp

≥300 °C

solubility

formic acid:water (1:1): 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow

solubility

hydrochloric acid: soluble 5 M, clear to slightly hazy, colorless to faintly yellow-green

solubility

-

solubility

-

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

200

General description

Guanosine is an aromatic organic molecule and a purine nucleoside. It is present in the cerebrospinal fluid, intestinal cells, blood-brain barrier and in brain microvessels.

Application

Guanosine has been used:
  • as a reference standard for the analysis of glucosinolates by high-performance liquid chromatography with diode-array detection and electrospray ionization tandem mass spectrometry (HPLC-DAD-ESI/MS)
  • as a component of Mouse Embryonic Fibroblasts (MEFs) culture
  • as a standard for the detection of residual RNA contaminant in oil palm plant genome samples by HPLC

Biochem/physiol Actions

Guanosine nucleoside elicits cellular effect as the guanine-based purinergic system. It modulates glutamate uptake by glutamate transporters. It may have neuroprotective functionality in central nervous system disorders. Guanosine promotes neurite arborization, outgrowth, proliferation and differentiation. Administration of guanosine replenished GTP and elicits protective function in renal ischemic injury.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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