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G6779

Sigma-Aldrich

Guanine

BioUltra

Synonym(s):

2-Amino-1,7-dihydro-6H-purin-6-one, 2-Amino-6-hydroxypurine, 2-Aminohypoxanthine

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About This Item

Empirical Formula (Hill Notation):
C5H5N5O
CAS Number:
73-40-5
Molecular Weight:
151.13
Beilstein/REAXYS Number:
9680
EC Number:
200-799-8
MDL number:
MFCD00071533
UNSPSC Code:
41106305
PubChem Substance ID:
24895274
NACRES:
NA.51

biological source

synthetic (organic)

product line

BioUltra

assay

≥99% (HPLC)

form

powder

impurities

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

mp

>300 °C (lit.)

solubility

1 M NaOH: 0.1 M, clear, colorless to faintly yellow

cation traces

Al: ≤0.02%
Ca: ≤0.005%
Cu: ≤0.0005%
Fe: ≤0.005%
K: ≤0.005%
Mg: ≤0.005%
Na: ≤0.1%
Pb: ≤0.001%
Zn: ≤0.002%

SMILES string

NC1=Nc2[nH]cnc2C(=O)N1

InChI

1S/C5H5N5O/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11)

InChI key

UYTPUPDQBNUYGX-UHFFFAOYSA-N

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Related Categories

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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S Kawanishi et al.
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Reactive species generated by chemicals and UV radiation can cause sequence-specific DNA damage and play important roles in mutagenesis, carcinogenesis and aging. We have investigated sequence specificity of oxidative stress-mediated DNA damage by using 32P-labeled DNA fragments obtained from the
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In single-group studies, chromosomal rearrangements of the anaplastic lymphoma kinase gene (ALK) have been associated with marked clinical responses to crizotinib, an oral tyrosine kinase inhibitor targeting ALK. Whether crizotinib is superior to standard chemotherapy with respect to efficacy is
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