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G7251

Glycine anhydride

≥99% (TLC)

Synonym(s):

2,5-Diketopiperazine, 2,5-Piperazinedione

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About This Item

Empirical Formula (Hill Notation):
C4H6N2O2
CAS Number:
Molecular Weight:
114.10
NACRES:
NA.26
PubChem Substance ID:
eCl@ss:
32160406
UNSPSC Code:
12352209
EC Number:
203-411-5
MDL number:
Beilstein/REAXYS Number:
112112
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Product Name

Glycine anhydride, cyclic dipeptide

assay

≥99% (TLC)

form

powder

color

white

mp

>300 °C (lit.)

SMILES string

O=C1CNC(=O)CN1

InChI

1S/C4H6N2O2/c7-3-1-5-4(8)2-6-3/h1-2H2,(H,5,8)(H,6,7)

InChI key

BXRNXXXXHLBUKK-UHFFFAOYSA-N

Application


  • Oxidation of cyclic dipeptides by photoinduced H-atom abstraction. A laser flash FT EPR and optical spectroscopy study.: The study examines the oxidation processes of cyclic dipeptides, focusing on the role of glycine anhydride in photoinduced hydrogen atom abstraction reactions (Tarábek et al., 2007).


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This Item
D160008759368320609
form

powder

form

solid

form

solid

form

powder

assay

≥99% (TLC)

assay

99%

assay

97%

assay

-

color

white

color

-

color

-

color

faint yellow

Quality Level

200

Quality Level

100

Quality Level

100

Quality Level

200

mp

>300 °C (lit.)

mp

144-146 °C (lit.)

mp

98-103 °C

mp

195 °C (dec.) (lit.)


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Liyun Zhang et al.
Amino acids, 43(1), 279-287 (2011-09-16)
Cyclic dipeptides, due to their chemical properties and various bioactivities, are very attractive for medicinal chemistry. Fragmentations of three simple cyclic dipeptides including cyclo(Gly-Gly), cyclo(Ala-Ala) and cyclo(Gly-Val) in the gas-phase are determined with synchrotron vacuum ultraviolet (VUV) photoionization mass spectrometry
R Shukla et al.
Peptides, 15(8), 1471-1474 (1994-01-01)
Central administration of exogenous cyclo(His-Pro) (CHP) is known to produce hypothermia in rodents. In the present study, we examined the role of endogenous CHP in cold-induced hypothermia in the desert rat, Mastomys natalensis. The results of these studies show that
M Prudel et al.
Die Nahrung, 29(4), 381-389 (1985-01-01)
A HPLC method for the determination of Usal (Aspartame hydrochloride, L-aspartyl-L-phenylalanine methyl ester hydrochloride) and its decomposition products was elaborated. Aspartic acid, phenylalanine, phenylalanine methyl ester, aspartyl-phenylalanine, phenylalanyl-aspartic acid, 5-benzyl-3,6-dioxo-2-piperazineacetic acid (DOP) and Usal were separated on Separon SI C-18.



Global Trade Item Number

SKUGTIN
G7251-25G04061833642610
G7251-100G04061832888699
G7251-1KG04061833642603

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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