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G7384

Sigma-Aldrich

Gallic acid

97.5-102.5% (titration)

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Synonym(s):
3,4,5-Trihydroxybenzoic acid
Linear Formula:
(HO)3C6H2CO2H
CAS Number:
Molecular Weight:
170.12
Beilstein/REAXYS Number:
2050274
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

97.5-102.5% (titration)

technique(s)

HPLC: suitable

mp

251 °C (dec.) (lit.)

suitability

suitable for UV spectrophotometry and general use
suitable for absorption spectrum analysis

application(s)

agriculture
metabolomics
microbiology
vitamins, nutraceuticals, and natural products
vitamins, nutraceuticals, and natural products

SMILES string

OC(=O)c1cc(O)c(O)c(O)c1

InChI

1S/C7H6O5/c8-4-1-3(7(11)12)2-5(9)6(4)10/h1-2,8-10H,(H,11,12)

InChI key

LNTHITQWFMADLM-UHFFFAOYSA-N

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1 of 4

This Item
PHR231891215398225
vibrant-m

G7384

Gallic acid

vibrant-m

PHR2318

Propyl Gallate Impurity A

vibrant-m

91215

Gallic acid

vibrant-m

398225

Gallic acid monohydrate

Quality Level

200

Quality Level

300

Quality Level

300

Quality Level

200

application(s)

agriculture
metabolomics
microbiology
vitamins, nutraceuticals, and natural products
vitamins, nutraceuticals, and natural products

application(s)

-

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

application(s)

-

technique(s)

HPLC: suitable

technique(s)

-

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

mp

251 °C (dec.) (lit.)

mp

251 °C (dec.) (lit.)

mp

251 °C (dec.) (lit.)

mp

252 °C (dec.) (lit.)

suitability

suitable for UV spectrophotometry and general use

suitability

-

suitability

-

suitability

-

General description

Gallic acid, also known as 3,4,5-Trihydroxybenzoic acid, is a natural polyhydroxyphenolic compound commonly found in many fruits and plants, including grapes, tea, and oak bark, either in the free acid form or esterified as gallotannins and ellagitannins. Existing research suggests that this plant-derived metabolite is an astringent, a cyclooxygenase-2 (COX-2) and histone acetyltransferase inhibitor, and an apoptosis inducer with various biological activities. These activities include antioxidant, antifungal, gastroprotective, neuroprotective, cardioprotective, antimicrobial, anti-inflammatory, anti-tumor, anti-tyrosinase, and anticancer effects.

Application

Gallic acid has been used:
  • as a standard for the quantification of extractable phenolics by external calibration
  • as a standard to determine the total tannin content of oak root powder using the Folin-Ciocalteu method
  • as a phenolic acid to study it′s in vitro antiviral, antibacterial, cytotoxicity and antifungal activities

Gallic acid is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Biochem/physiol Actions

Gallic acid is a water soluble phenolic acid present in grapes and in the leaves of many plants. Gallic acid esters, such as tannins, catechin gallates and aliphatic gallates are potent antioxidants in vitro. However, gallic acid itself also appears to have antioxidant, anticarcinogenic and antiangiogenic activity in vitro.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves


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