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MilliporeSigma

G7403

Sigma-Aldrich

Glycine

≥99% (titration), suitable for electron microscopy, BioXtra

Synonym(s):

Aminoacetic acid, Aminoethanoic acid, Glycocoll

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100 G
$61.50
250 G
$113.00
1 KG
$340.00

About This Item

Linear Formula:
NH2CH2COOH
CAS Number:
Molecular Weight:
75.07
Beilstein/REAXYS Number:
635782
EC Number:
MDL number:
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

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$61.50


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Product Name

Glycine, BioXtra, ≥99% (titration)

product line

BioXtra

Quality Level

assay

≥99% (titration)

form

powder

technique(s)

electron microscopy: suitable

impurities

Insoluble matter, passes filter test

ign. residue

≤0.05%

loss

≤0.05% loss on drying, HV, 20-26 °C

color

white

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

solubility

1 M HCl: 1 M, clear, colorless

anion traces

chloride (Cl-): ≤0.005%
sulfate (SO42-): ≤0.005%

cation traces

Al: ≤0.0005%
As: ≤0.00001%
Ba: ≤0.0005%
Bi: ≤0.0005%
Ca: ≤0.001%
Cd: ≤0.0005%
Co: ≤0.0005%
Cr: ≤0.0005%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Li: ≤0.0005%
Mg: ≤0.0005%
Mn: ≤0.0005%
Mo: ≤0.0005%
NH4+: ≤0.02%
Na: ≤0.02%
Ni: ≤0.0005%
Pb: ≤0.0005%
Sr: ≤0.0005%
Zn: ≤0.0005%

absorption

≤0.04 at 260 in 1 M HCl at 1 M
≤0.04 at 280 in 1 M HCl at 1 M

SMILES string

NCC(O)=O

UV absorption

λ: 260 nm Amax: ≤0.04
λ: 260 nm Amax: 0.003
λ: 260 nm Amax: 0.006

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

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G7126G87901.03669
Glycine BioXtra, ≥99% (titration)

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Glycine ReagentPlus®, ≥99% (HPLC)

G7126

Glycine

Glycine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%

G8790

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Glycine granulated, EMPROVE® EXPERT, Ph. Eur., BP, ChP, JP, USP

1.03669

Glycine

form

powder

form

powder

form

powder

form

granular

technique(s)

electron microscopy: suitable

technique(s)

western blot: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

inhibition assay: suitable

assay

≥99% (titration)

assay

≥99% (HPLC)

assay

≥98.5%

assay

99.0-101.0% (calculated on dried substance, perchloric acid titration)

product line

BioXtra

product line

ReagentPlus®

product line

-

product line

EMPROVE® EXPERT

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

color

white

color

white to off-white

color

white

color

-

Application

Glycine has been used to quench unreacted aldehyde during sample (nuclei) preparation for scanning electron microscope.[1] It has also been used for sample fixation in the process of immunolabeling.[2]

Biochem/physiol Actions

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.
Glycine is a non-essential amino acid.[3] Influx of calcium through the cell membrane is mediated by glycine-gated channel. Glycine participates in the synthesis of porphyrins, purine and serine. It also serves as a competitive agonist for glutamate in binding to the NMDA (N-methyl-D-aspartate) receptors.[4] Glycine synthesis might be increased in rapidly proliferating cancer cells, due to increased demand for the amino acid.[3]

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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