G8541

Sigma-Aldrich

Ala-Gln

200 mM, solution, sterile-filtered, Biotechnology Performance Certified

Synonym(s):
Alanyl-glutamine, Glutamine-S
Empirical Formula (Hill Notation):
C8H15N3O4
CAS Number:
Molecular Weight:
217.22
MDL number:
PubChem Substance ID:

grade

Biotechnology Performance Certified

Quality Level

sterility

sterile-filtered

form

solution

concentration

200 mM

impurities

endotoxin, tested

storage temp.

2-8°C

SMILES string

NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O

InChI

1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1

InChI key

HJCMDXDYPOUFDY-WHFBIAKZSA-N

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Application

This supplement provides a stable form of L-glutamine while in solution.

Other Notes

Contains the dipeptide L-Alanyl-L-glutamine. 200 mM supplied in 0.85% NaCl.

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

A I Gonçalves et al.
Journal of tissue engineering and regenerative medicine, 12(3), 762-774 (2017-06-09)
Cell-based therapies are of particular interest for tendon and ligament regeneration given the low regenerative potential of these tissues. Adipose tissue is an abundant source of stem cells, which may be employed for the healing of tendon lesions. However, human...
Yu-Chen Hou et al.
The Journal of nutritional biochemistry, 24(9), 1555-1563 (2013-03-23)
Regulatory T cells (Tregs) and T helper (Th) 17 cells are two subsets of Th cells with opposing actions which participate in the process of resolving acute lung injury (ALI). Glutamine (Gln) is a nutrient commonly used in nutrition regimens...
Dieter Fink et al.
PloS one, 14(11), e0224576-e0224576 (2019-11-08)
Intra-bone marrow transplantation (IBMT) has been adapted for mouse models to improve the seeding efficiency of transplanted hematopoietic stem and progenitor cells. Commonly used injection volumes for IBMT into the tibia differ between 10 and 40 μL even though considerable...
Daren K Heyland et al.
JPEN. Journal of parenteral and enteral nutrition, 39(4), 401-409 (2014-05-08)
The recent large randomized controlled trial of glutamine and antioxidant supplementation suggested that high-dose glutamine is associated with increased mortality in critically ill patients with multiorgan failure. The objectives of the present analyses were to reevaluate the effect of supplementation...
Bente K Hansen et al.
Structure (London, England : 1993), 28(5), 528-539 (2020-03-30)
Phenomycin is a bacterial mini-protein of 89 amino acids discovered more than 50 years ago with toxicity in the nanomolar regime toward mammalian cells. The protein inhibits the function of the eukaryotic ribosome in cell-free systems and appears to target translation...
Articles
Importance and uses of glutamine in hybridoma and mammalian cell culture
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Organoid culture products to generate tissue and stem cell derived 3D brain, intestinal, gut, lung and cancer tumor organoid models.
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