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G8876

Sigma-Aldrich

Glycogen from rabbit liver

≥85% dry basis (enzymatic)

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CAS Number:
9005-79-2
EC Number:
232-683-8
MDL number:
MFCD00081547
NACRES:
NA.25

biological source

rabbit liver

Quality Level

200

Assay

≥85% dry basis (enzymatic)

form

powder

color

white to off-white

solubility

water: 40 mg/mL, clear to turbid, colorless to light yellow

storage temp.

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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Glycogen from rabbit liver ≥85% dry basis (enzymatic)

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Glycogen from oyster ≥75% dry basis

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G8751

Glycogen from oyster

assay

≥85% dry basis (enzymatic)

assay

≥85%

assay

-

assay

≥75% dry basis

form

powder

form

powder

form

liquid

form

powder

color

white to off-white

color

white to off-white

color

-

color

white to off-white

solubility

water: 40 mg/mL, clear to turbid, colorless to light yellow

solubility

-

solubility

-

solubility

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

  • Glycogen from rabbit liver has been use as a standard for measurement of the hepatic glycogen content.
  • In the1,4-α-D gIucan:orthophosphate α-glucosyl transferase assay, it has been used in the assay mixture.
  • It has also been used as a standard for myocardial tissue glycogen analysis.

Biochem/physiol Actions

Glycogen from rabbit liver helps in maintaining blood glucose levels by regulating the release of glucose in between meals. It also provides energy during sudden, strenuous activity. Two important areas of glycogen storage are the liver and skeletal muscle.

Preparation Note

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M A Brooks et al.
Poultry science, 95(5), 1096-1104 (2016-03-05)
The objective of this study was to evaluate the effects of dietary chromium (Cr), as chromium propionate, on measures of insulin sensitivity. Liver and muscle glycogen, and plasma glucose and non-esterified fatty acid (NEFA) concentrations were used as indicators of
Glycogen Metabolism
Berg JM, et al.
Biochemistry (2002)
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, et al.
Experimental Biology and Medicine (Maywood, N.J.), 231, 566-575 (2006)
Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output to the liver.
Cailotto C, et al.
Endocrinology, 149, 1914-1925 (2008)
Relationship between beta-adrenergic receptor numbers and physiological responses during experimental canine myocardial ischemia.
Mukherjee A, et al.
Circulation Research, 50, 735-741 (1982)
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