G8876

Sigma-Aldrich

Glycogen from rabbit liver

≥85% dry basis (enzymatic)

CAS Number:
EC Number:
MDL number:
NACRES:
NA.25

Quality Level

biological source

rabbit liver

assay

≥85% dry basis (enzymatic)

form

powder

storage temp.

2-8°C

InChI

1S/C24H42O21/c25-1-5-9(28)11(30)16(35)22(41-5)39-4-8-20(45-23-17(36)12(31)10(29)6(2-26)42-23)14(33)18(37)24(43-8)44-19-7(3-27)40-21(38)15(34)13(19)32/h5-38H,1-4H2/t5-,6-,7-,8-,9-,10-,11+,12+,13-,14-,15-,16-,17-,18-,19-,20-,21+,22+,23-,24-/m1/s1

InChI key

BYSGBSNPRWKUQH-UJDJLXLFSA-N

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General description

Glycogen is a branched polymer of glucose synthesized by animal cells for energy storage and release. It is constructed of predominantly α1→4 glycosidic bonds with branches created through α1→6 glycosidic bonds.

Application

  • Glycogen from rabbit liver has been use as a standard for measurement of the hepatic glycogen content.
  • In the1,4-α-D gIucan:orthophosphate α-glucosyl transferase assay, it has been used in the assay mixture.
  • It has also been used as a standard for myocardial tissue glycogen analysis.

Packaging

500 mg in poly bottle
1, 5, 10 g in poly bottle

Biochem/physiol Actions

Glycogen from rabbit liver helps in maintaining blood glucose levels by regulating the release of glucose in between meals. It also provides energy during sudden, strenuous activity. Two important areas of glycogen storage are the liver and skeletal muscle.

Preparation Note

Prepared by a modification of the procedure of Bell, et al., Biochem. J., 28, 882 (1934).

storage_class_code

13 - Non Combustible Solids

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Janne R Hingst et al.
Molecular metabolism, 16, 24-34 (2018-08-11)
A single bout of exercise followed by intake of carbohydrates leads to glycogen supercompensation in prior exercised muscle. Our objective was to illuminate molecular mechanisms underlying this phenomenon in skeletal muscle of man. We studied the temporal regulation of glycogen...
Daily rhythms in metabolic liver enzymes and plasma glucose require a balance in the autonomic output to the liver.
Cailotto C, et al.
Endocrinology, 149, 1914-1925 (2008)
M A Brooks et al.
Poultry science, 95(5), 1096-1104 (2016-03-05)
The objective of this study was to evaluate the effects of dietary chromium (Cr), as chromium propionate, on measures of insulin sensitivity. Liver and muscle glycogen, and plasma glucose and non-esterified fatty acid (NEFA) concentrations were used as indicators of...
Developmental changes in ovine myocardial glucose transporters and insulin signaling following hyperthermia-induced intrauterine fetal growth restriction.
Barry JS, et al.
Experimental Biology and Medicine (Maywood, N.J.), 231, 566-575 (2006)
Glycogen Metabolism
Berg JM, et al.
Biochemistry (2002)
Articles
Glucose metabolism is regulated by the opposing actions of insulin and glucagon. Insulin is released from pancreatic ß cells in response to high blood glucose levels and regulates glucose metabolism through its actions on muscle, liver, and adipose tissue.
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