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GW21186

Sigma-Aldrich

Anti-CDH1 antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

Synonym(s):
Anti-Epithelial-cadherin, Anti-Cadherin-1
MDL number:

biological source

chicken

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

human, rat, mouse

manufacturer/tradename

Genway 15-288-21186

application(s)

western blot: suitable

conjugate

unconjugated

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... CDH1(999)

Immunogen

Recombinant cadherin 1, type 1 preproprotein
Immunogen Sequence: GI # 4757960, sequence 441-523

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Certificate of Analysis

Certificate of Origin

Zhen-Hai Lin et al.
International journal of oncology, 45(2), 629-640 (2014-05-27)
Mammalian sterile-20-like kinase 4 (MST4) has been implicated in cell proliferation and differentiation. In a previous study, we found MST4 to be an important candidate gene for metastatic hepatocellular carcinoma (HCC); however, the molecular mechanism of the promoting role of...
Renata Bordeira-Carriço et al.
European journal of human genetics : EJHG, 22(9), 1085-1092 (2014-01-16)
Hereditary diffuse gastric cancer (HDGC) syndrome, although rare, is highly penetrant at an early age, and is severe and incurable because of ineffective screening tools and therapy. Approximately 45% of HDGC families carry germline CDH1/E-cadherin alterations, 20% of which are...
Rui Du et al.
Molecular biology of the cell, 25(17), 2650-2659 (2014-07-11)
Hypoxia is an important microenvironmental factor in the development of renal fibrosis; however, the underlying mechanisms are not well elucidated. Here we show that hypoxia induces Bmi1 mRNA and protein expression in human tubular epithelial cells. We further demonstrate that...
Eirini Pectasides et al.
PloS one, 9(4), e94273-e94273 (2014-04-12)
Elucidating the molecular phenotype of cancers with high metastatic potential will facilitate the development of novel therapeutic approaches to the disease. Gene expression profiles link epithelial to mesenchymal transition (EMT) phenotype with high-risk HNSCC. We sought to determine the role...
Yiru Wang et al.
International journal of molecular medicine, 33(6), 1514-1522 (2014-03-29)
Forkhead box M1 (FoxM1) transcription factor is related to the pathogenesis of various malignancies and recent evidence indicates that FoxM1 promotes epithelial-mesenchymal transition (EMT) in breast cancer. Metformin can inhibit the progression of cancer. However, whether FoxM1 plays a role...

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