GW22766

Anti-FAS (ab1) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

• Synonym(s): Anti-CD95
• MDL number: MFCD00283209

Properties

• biological source: chicken
• Quality Level: 200
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human, mouse, rat
• manufacturer/tradename: Genway 15-288-22766
• technique(s): western blot: suitable
• NCBI accession no.: NP_000034.1
• UniProt accession no.: P25445
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... FAS(355)

Description

General description

The FAS receptor (FasR) is a protein encoded by the TNFRSF6 gene in humans and is mapped to chromosomal band 10q24.1. It is a cell surface antigen expressed on a variety of normal and malignant cells.

Immunogen

Immunogen Sequence: GI # 4507583, sequence 21-165

Recombinant tumor necrosis factor receptor superfamily, member 6 isoform 1

Application

Anti-FAS (ab1) antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

The FAS receptor (FasR) is associated with programmed cell death (apoptosis). It functions as an apoptosis-signaling cell surface Ag. Mutation of the gene or defective FAS signaling may render the T-cell lymphoblastic lymphomas (T-LBLs) tumor cells resistant to apoptotic cell death.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves