This product is not packaged in tablets, it is a supplied in powdered format. It is currently offered in a 25 mg and 100 mg pack size.
H0392
Hemoglobin S, Ferrous Stabilized human
lyophilized powder
Synonym(s):
Sickle cell hemoglobin
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About This Item
Form:
lyophilized powder
Assay:
97-100% (agarose gel electrophoresis)
Biological source:
human
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biological source
human
assay
97-100% (agarose gel electrophoresis)
form
lyophilized powder
technique(s)
electrophoresis: suitable, immunofluorescence: suitable
solubility
H2O: soluble 20 mg/mL
suitability
suitable for electrophoresis and chromatography standard
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... HBB(3043)
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This Item | |||
|---|---|---|---|
| assay 97-100% (agarose gel electrophoresis) | assay 97-100% (agarose gel electrophoresis) | assay - | assay - |
| technique(s) electrophoresis: suitable, immunofluorescence: suitable | technique(s) immunofluorescence: suitable | technique(s) enzyme immunoassay: suitable | technique(s) activity assay: suitable |
| biological source human | biological source human | biological source human | biological source bovine blood |
| form lyophilized powder | form lyophilized powder | form lyophilized powder | form substrate powder |
| suitability suitable for electrophoresis and chromatography standard | suitability suitable for electrophoresis and chromatography standard | suitability - | suitability suitable for protease substrate |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
General description
Hemoglobin is the major component of red blood cells, and is responsible for their red color. Its normal concentration in erythrocytes is 34%. Hemoglobin is the most important respiratory protein of vertebrates by virtue of its ability to transport oxygen from the lungs to body tissues, and to facilitate the return transport of carbon dioxide.
has not been tested for functional equivalence against native preparations (unlyophilized ferrous hemoglobins).
Application
Hemoglobin S was used in the determination of fetal hemoglobin by time-resolved immunofluorometric assay.[1]
Packaging
Package size indicates the amount of hemoglobin as determined by the procedure of Drabkin, D.L., J. Biol. Chem., 164, 703 (1946).
Preparation Note
When reconstituted with buffer, gives >90% ferrous hemoglobin.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Brian T Castle et al.
Science advances, 5(3), eaau1086-eaau1086 (2019-03-21)
In sickle cell disease, the aberrant assembly of hemoglobin fibers induces changes in red blood cell morphology and stiffness, which leads to downstream symptoms of the disease. Therefore, understanding of this assembly process will be important for the treatment of
U Turpeinen et al.
Clinical chemistry, 38(10), 2013-2018 (1992-10-01)
We have developed a "sandwich"-type time-resolved immunofluorometric assay (IFMA) for fetal hemoglobin (HbF) in hemolysates from adults and newborns, amniotic fluid, and plasma, based on a polyclonal and a monoclonal antibody against human fetal hemoglobin. Microtiter wells are coated with
Charles T Quinn et al.
British journal of haematology, 175(4), 724-732 (2016-09-09)
Sickle cell disease (SCD) is a significant healthcare burden worldwide, but most affected individuals reside in low-resource areas where access to diagnostic testing may be limited. We developed and validated a rapid, inexpensive, disposable diagnostic test, the HemoTypeSC™ , based
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