H0527

Sigma-Aldrich

HEPES potassium salt

≥99.5% (titration)

Synonym(s):
N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) potassium salt, 4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid potassium salt
Empirical Formula (Hill Notation):
C8H17KN2O4S
CAS Number:
Molecular Weight:
276.39
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

assay

≥99.5% (titration)

form

powder

useful pH range

6.8 - 8.2

pKa 

7.5

solubility

water: 0.5 g/mL, clear, colorless

SMILES string

[K+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.K/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI key

KWURIFKZTJGMFD-UHFFFAOYSA-M

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Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Y M Nuwan D Y Bandara et al.
Nanotechnology, 31(33), 335707-335707 (2020-05-02)
Solid-state nanopores (SSNs) are single-molecule resolution sensors with a growing footprint in real-time bio-polymer profiling-most prominently, but far from exclusively, DNA sequencing. SSNs accessibility has increased with the advent of controlled dielectric breakdown (CDB), but severe fundamental challenges remain: drifts...
Jugal Saharia et al.
ACS nano, 13(4), 4246-4254 (2019-03-08)
In this study, we investigated the voltage and pH responsiveness of human serum transferrin (hSTf) protein using silicon nitride (Si xN y) nanopores. The Fe(III)-rich holo form of hSTf was dominant when pH > pI, while the Fe(III)-free apo form...
Neha Tiwari et al.
Cell stem cell, 23(4), 557-571 (2018-10-06)
A broad molecular framework of how neural stem cells are specified toward astrocyte fate during brain development has proven elusive. Here we perform comprehensive and integrated transcriptomic and epigenomic analyses to delineate gene regulatory programs that drive the developmental trajectory...

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