All Photos(5)

H3784

Sigma-Aldrich

HEPES sodium salt

BioPerformance Certified, suitable for cell culture, ≥99.5%

Synonym(s):
4-(2-Hydroxyethyl)piperazine-1-ethanesulfonic acid sodium salt, N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) sodium salt
Empirical Formula (Hill Notation):
C8H17N2NaO4S
CAS Number:
Molecular Weight:
260.29
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

grade

BioPerformance Certified

Quality Level

assay

≥99.5%

form

powder

application(s)

cell culture | mammalian: suitable

impurities

endotoxin and total aerobic microbial count, tested

pH

10-12 (1 M in water)

useful pH range

6.8 - 8.2

pKa (25 °C)

7.5

solubility

water: 0.1 M, clear, colorless (260 mg/mL)

absorption

≤0.02 at 280 in H2O at 0.1 M
≤0.04 at 260 in H2O at 0.1 M

Featured Industry

Diagnostic Assay Manufacturing

foreign activity

DNase, RNase, NICKase, protease, none detected

SMILES string

[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O

InChI

1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI key

RDZTWEVXRGYCFV-UHFFFAOYSA-M

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Related Categories

Packaging

25, 100, 500 g in poly bottle
1 kg in poly bottle

Physical form

Lyophilized, spray dried, or crystallized material.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Mingyue Li et al.
Structure (London, England : 1993), 27(5), 806-815 (2019-03-19)
The peroxidation of cardiolipins by reactive oxygen species, which is regulated and enhanced by cytochrome c (cyt c), is a critical signaling event in mitochondrial apoptosis. We probe the molecular underpinnings of this mitochondrial death signal through structural and functional...
Ekaterina Isaac et al.
Theriogenology, 161, 273-284 (2020-12-29)
The growth of viable cattle embryos in culture to stages beyond the hatching blastocyst is of interest to developmental biologists wishing to understand developmental events beyond the first lineage decision, as well as for commercial applications, because a lengthening of...
Artem Babaian et al.
Cell reports, 31(5), 107611-107611 (2020-05-07)
The ribosome is an RNA-protein complex that is essential for translation in all domains of life. The structural and catalytic core of the ribosome is its ribosomal RNA (rRNA). While mutations in ribosomal protein (RP) genes are known drivers of...
Ines Rosignol et al.
International journal of molecular sciences, 21(5) (2020-03-14)
Mitochondrial damage plays a prominent role in glaucoma. The only way cells can degrade whole mitochondria is via autophagy, in a process called mitophagy. Thus, studying mitophagy in the context of glaucoma is essential to understand the disease. Up to...
Satyabrata Das et al.
Nature biotechnology, 38(3), 297-302 (2020-02-26)
The scarcity of donor organs may be addressed in the future by using pigs to grow humanized organs with lower potential for immunological rejection after transplantation in humans. Previous studies have demonstrated that interspecies complementation of rodent blastocysts lacking a...

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