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H4522

Sigma-Aldrich

Human Serum

from human male AB plasma, USA origin, sterile-filtered

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Synonym(s):
human plasma, human sera, human serum
MDL number:
NACRES:
NA.71

biological source

human male plasma (Type AB)

Quality Level

sterility

sterile-filtered

composition

hemoglobin, ≤30 mg/dL

origin

USA origin

technique(s)

cell culture | mammalian: suitable
cell culture | stem cell: suitable

impurities

≤10 EU/mL endotoxin

shipped in

dry ice

storage temp.

−20°C

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This Item
H3667H6914H5667
Human Serum from human male AB plasma, USA origin, sterile-filtered

Sigma-Aldrich

H4522

Human Serum

Human Serum Heat Inactivated, from human male AB plasma, USA origin, sterile-filtered

Sigma-Aldrich

H3667

Human Serum

Human Serum (from male AB clotted whole blood), USA origin, sterile-filtered

Sigma-Aldrich

H6914

Human Serum

Human Serum Heat Inactivated (from male AB clotted whole blood), USA origin, sterile-filtered

Sigma-Aldrich

H5667

Human Serum

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile-filtered

sterility

sterile-filtered

composition

hemoglobin, ≤30 mg/dL

composition

hemoglobin, ≤20 mg/dL

composition

Hemoglobin, ≤25 mg/dL

composition

Hemoglobin, ≤25 mg/dL

origin

USA origin

origin

USA origin

origin

USA origin

origin

USA origin

technique(s)

cell culture | mammalian: suitable, cell culture | stem cell: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable, cell culture | stem cell: suitable

technique(s)

cell culture | mammalian: suitable, cell culture | stem cell: suitable

impurities

≤10 EU/mL endotoxin

impurities

≤10 EU/mL endotoxin

impurities

≤10 EU/mL Endotoxin

impurities

≤10 EU/mL Endotoxin

Application

Human AB serum is used in tissue engineering, transplantation and cell therapy applications for the expansion of mesenchymal stem cells (MSC) from adipose tissue or mesenchymal stromal cells from human bone marrow; for standardized limbal epithelial stem cell graft generation and transplantation; for ex vivo expansion of NK cells from peripheral blood in Hematopoeitic Stem Cell Expansion Medium; and for upgrading pretransplant human islet culture technology.
Human Serum has been used: as a component of phosphate-buffered saline with Tween® detergent (PBST) in bridging enzyme-linked immunosorbent assay (ELISA), as a mock biological sample for assessing the performance of paper-based ELISA assay with complex biological samples, as a diluent to create a dilution series of the baseline sample for the generation of standard curve for NISTmAb spiked into serum, as well as for multiple myeloma (MM) patient sample MM2232

Biochem/physiol Actions

Human AB serum is typically obtained by allowing whole blood to clot naturally, which is known as Off-The-Clot (OTC) serum. Human serum obtained from clotted whole blood is preferred as it usually contains higher levels and a more diverse range of growth factors for optimal cell growth. Human serum from blood-type AB donors lacks antibodies specific for both A and B blood-type antigens. This makes it a universal donor serum that is suitable for various cell culture types including human stem cell lines.

Packaging

Packaging may vary for different batches due to short supply of the bottles used to pack this product. The presence or lack of shrink wrap around the cap of the bottle doesn’t impact product integrity/sterility of the product.

Warning

Each donor is tested for and found non-reactive for Hepatitis B & C and non-reactive for Human Immunodeficiency Virus (HIV) antibody by ELISA. Nevertheless, products of human origin should be considered potentially infectious and handled accordingly.

Analysis Note

Endotoxin tested

Other Notes

It is not unusual for our human serum products to be cloudy. This product is from pooled serum and cloudiness indicates that lipids are present in the serum. No clear, lipid-free human serum products are available.

Legal Information

TWEEN is a registered trademark of Croda International PLC

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

related product

Product No.
Description
Pricing

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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