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H6647

L-Histidinol dihydrochloride

≥98% (TLC)

Synonym(s):

β-Aminoimidazole-4-propanol dihydrochloride, (S)-2-Amino-3-(4-imidazolyl)propanol dihydrochloride

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10 MG

$43.10

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$214.00

5 G

$717.40

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About This Item

Empirical Formula (Hill Notation):
C6H11N3O · 2HCl
CAS Number:
1596-64-1
Molecular Weight:
214.09
NACRES:
NA.32
PubChem Substance ID:
24895755
UNSPSC Code:
12352209
EC Number:
216-482-2
MDL number:
MFCD00078058
Beilstein/REAXYS Number:
3914853

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Product Name

L-Histidinol dihydrochloride, ≥98 (TLC)

InChI key

FRCAFNBBXRWXQA-XRIGFGBMSA-N

InChI

1S/C6H11N3O.2ClH/c7-5(3-10)1-6-2-8-4-9-6;;/h2,4-5,10H,1,3,7H2,(H,8,9);2*1H/t5-;;/m0../s1

SMILES string

Cl[H].Cl[H].N[C@H](CO)Cc1c[nH]cn1

assay

≥98% (TLC)

form

powder

color

white to off-white

mp

198-201 °C (dec.) (lit.)

application(s)

cell analysis

Quality Level

200

Gene Information

human ... HRH1(3269)
mouse ... HRH1(15465)
rat ... HRH1(24448)

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1 of 4

This Item
H3751H800053300
L-Histidinol dihydrochloride ≥98 (TLC)

Sigma-Aldrich

H6647

L-Histidinol dihydrochloride

D-Histidine ≥98% (TLC)

Sigma-Aldrich

H3751

D-Histidine

L-Histidine ReagentPlus®, ≥99% (TLC)

Sigma-Aldrich

H8000

L-Histidine

Histamine dihydrochloride ≥99.0% (AT)

Sigma-Aldrich

53300

Histamine dihydrochloride

form

powder

form

powder

form

powder

form

powder or crystals

assay

≥98% (TLC)

assay

≥98% (TLC)

assay

≥99% (TLC)

assay

≥99.0% (AT)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

mp

198-201 °C (dec.) (lit.)

mp

280 °C

mp

282 °C (dec.) (lit.)

mp

244-247 °C, 249-252 °C (lit.)

color

white to off-white

color

white

color

white to off-white

color

-

application(s)

cell analysis

application(s)

detection
peptide synthesis

application(s)

cell analysis

application(s)

-

Application

L-Histidinol dihydrochloride has been used:
  • as a reagent in urinary metabolite analysis[1]
  • for making DT40 knockout cells, where cells were selected in 1mg/ml histidinol[2]
  • for inducing amino acid deprivation in HepG2 cells[3]

Biochem/physiol Actions

Precursor of histamine; reversible inhibitor of protein synthesis.

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
0000487044
0000487067
0000487120
0000487044
0000487120

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David G Meckes et al.
Virology, 398(2), 208-213 (2010-01-07)
The conserved UL16 tegument protein of herpes simplex virus exhibits dynamic capsid-binding properties with a release mechanism that is triggered during initial virus attachment events. In an effort to understand the capsid association and subsequent release of UL16, we sought
R C Warrington
Biochemistry and cell biology = Biochimie et biologie cellulaire, 70(5), 365-375 (1992-05-01)
Human cancer chemotherapy is limited by two major problems: the failure of commonly used anticancer drugs to act against tumor cells in a specific manner and the ability of malignant cells to resist killing by antineoplastic agents. Experimentally, both of
Fouzia Sadiq et al.
Nutrition & metabolism, 5, 5-5 (2008-02-14)
Intravenous infusions of glucose and amino acids increase both nitrogen balance and muscle accretion. We hypothesised that co-infusion of glucose (to stimulate insulin) and essential amino acids (EAA) would act additively to improve nitrogen balance by decreasing muscle protein degradation
Ravi K Dinesh et al.
European journal of immunology, 50(3), 380-395 (2019-12-11)
Secondary diversification of the Ig repertoire occurs through somatic hypermutation (SHM), gene conversion (GCV), and class switch recombination (CSR)-three processes that are initiated by activation-induced cytidine deaminase (AID). AID targets Ig genes at orders of magnitude higher than the rest
Ana Luísa De Sousa-Coelho et al.
Journal of lipid research, 54(7), 1786-1797 (2013-05-11)
Lipogenic gene expression in liver is repressed in mice upon leucine deprivation. The hormone fibroblast growth factor 21 (FGF21), which is critical to the adaptive metabolic response to starvation, is also induced under amino acid deprivation. Upon leucine deprivation, we
View All Related Papers

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