H6903

Sigma-Aldrich

HEPBS

≥99% (titration)

Synonym(s):
N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid)
Empirical Formula (Hill Notation):
C10H22N2O4S
CAS Number:
Molecular Weight:
266.36
MDL number:
NACRES:
NA.25
Pricing and availability is not currently available.

Quality Level

assay

≥99% (titration)

form

powder

pH range

7.6 - 9.0

useful pH range

7.6 - 9.0

pKa (25 °C)

8.3

pKa 

8.3

solubility

water: 0.5 g/mL, clear to slightly hazy, colorless to faintly yellow

Featured Industry

Diagnostic Assay Manufacturing

Related Categories

General description

HEPBS/N-(2-Hydroxyethyl)piperazine-N′-(4-butanesulfonic acid) is mainly used in buffer preparations.

Packaging

25, 100 g in poly bottle

Linkage

Homolog of HEPES and EPPS with higher pKa and similar utility in biological systems.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Target Organs

Respiratory system

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Template-Directed Synthesis in 3?-and 5?-Direction with Reversible Termination
Kaiser A, et al.
Angewandte Chemie (International Edition in English), 51(33), 8299-8303 (2012)
T Thiel et al.
Journal of biochemical and biophysical methods, 37(3), 117-129 (1998-12-31)
Four new zwitterionic butanesulfonic acid buffers that are structurally related to four families of Good buffers were evaluated for use in biological systems. These buffers, with pKa values from 7.6 to 10.7, were compared with a variety of other buffers...
Michael Bachmann et al.
Journal of cell science, 133(9) (2020-03-21)
αVβ3 integrin can bind to multiple extracellular matrix proteins, including vitronectin (Vn) and fibronectin (Fn), which are often presented to cells in culture as homogenous substrates. However, in tissues, cells experience highly complex and changing environments. To better understand integrin...

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