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H7750

Sigma-Aldrich

DL-Histidine

≥99% (TLC)

Synonym(s):
(±)-2-Amino-3-(4-imidazolyl)propionic acid
Empirical Formula (Hill Notation):
C6H9N3O2
CAS Number:
Molecular Weight:
155.15
Beilstein:
7800
EC Number:
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.26

Quality Level

assay

≥99% (TLC)

form

powder

application(s)

ligand binding assay: suitable
peptide synthesis: suitable

mp

273 °C (dec.) (lit.)

solubility

0.5 M HCl: soluble

SMILES string

NC(Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)

InChI key

HNDVDQJCIGZPNO-UHFFFAOYSA-N

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Application

DL-Histidine has been used to study the fouling behaviour of polyethersulfone ultrafiltration membranes made with different PVP (polyvinylpyrrolidone).
DL-Histidine is the mixed isomer of D- and L-histidine. DL-Histidine may be used to evaluate the efficiency of amino acid chiral ligand exchange media and systems and in running buffers for capillary electrophoresis.

Packaging

25, 100 g in poly bottle

Biochem/physiol Actions

L-Histidine is involved in the one-carbon unit metabolism. It is associated with protein methylation. L-Histidine is a part of hemoglobin structure and function. L-Histidine is a component of dipeptides with antioxidative property. Histidine serves as a precursor for the formation of histamine, which is associated with allergic responses. Urocanic acid, an immune response modulator in skin is also biosynthesised from histidine.

Storage Class Code

13 - Non Combustible Solids

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Fouling behaviour of polyethersulfone UF membranes made with different PVP
J.Marchese
Journal of Membrane Science , 211, 1-11 (2009)
Worapan Pormsila et al.
Electrophoresis, 32(8), 884-889 (2011-03-12)
The quantification of plasma lactate and evaluation of the lactate threshold by CE with capacitively coupled contactless conductivity is demonstrated. The only sample preparation needed was deproteinization with a ACN/methanol mixture. A solution of 10 mmol/L 2-morpholinoethanesulfonic acid monohydrate, 10...
Yoshikazu Tsukasaki et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(45), 16011-16016 (2014-10-31)
The cadherins Fat and Dachsous regulate cell polarity and proliferation via their heterophilic interactions at intercellular junctions. Their ectodomains are unusually large because of repetitive extracellular cadherin (EC) domains, which raises the question of how they fit in regular intercellular...
Ana E Zeraik et al.
International journal for parasitology, 44(8), 523-531 (2014-04-29)
Septins are guanosine-5'-triphosphate-binding proteins involved in wide-ranging cellular processes including cytokinesis, vesicle trafficking, membrane remodelling and scaffolds, and with diverse binding partners. Precise roles for these structural proteins in most processes often remain elusive. Identification of small molecules that inhibit...
Hai Zhou et al.
Nature communications, 5, 4884-4884 (2014-09-12)
Thermosensitive genic male-sterile (TGMS) lines, which are male-sterile at restrictive (high) temperatures but male-fertile at permissive (low) temperatures, have been widely used in breeding two-line hybrid rice (Oryza sativa L.). Here we find that mutation of thermosensitive genic male sterile...

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