Hexammine cobalt(III) chloride

for use in transformations, X-ray crystallography and NMR

Cobalt hexammine trichloride, Hexaamminecobalt trichloride
Linear Formula:
CAS Number:
Molecular Weight:
EC Number:
MDL number:
PubChem Substance ID:

Quality Level


for molecular biology



storage temp.

room temp

SMILES string




InChI key


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General description

Hexammine cobalt(III) is considered an analog of fully solvated magnesium, capable of activating some enzymes that requires magnesium. It is useful in DNA condensation studies.


Suitable for
  • DNA condensation studies
  • induction of transitions of DNA from B to A or Z forms
  • induction of nucleic acid crystal growth
  • stabilization of tertiary tRNA interactions
  • preparation of ligation buffer


5, 10, 25 g in poly bottle


Health hazard

Signal Word


Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

J S Kieft et al.
Structure (London, England : 1993), 5(5), 713-721 (1997-05-15)
Solvated metal ions are critical for the proper folding and function of RNA. Despite the importance of these ions, the details of specific metal ion-RNA interactions are poorly understood. The crystal structure of a group I intron ribozyme domain characterized...
Meredith Newby Lambert et al.
RNA (New York, N.Y.), 11(11), 1688-1700 (2005-10-26)
Helix (H)27 from Escherichia coli 16S ribosomal (r)RNA is centrally located within the small (30S) ribosomal subunit, immediately adjacent to the decoding center. Bacterial 30S subunit crystal structures depicting Mg(2+) binding sites resolve two magnesium ions within the vicinity of...
M C Whitby et al.
The Journal of biological chemistry, 273(31), 19729-19739 (1998-07-25)
The RecG protein of Escherichia coli is a junction-specific DNA helicase that drives branch migration of Holliday intermediates in genetic recombination and DNA repair. The reaction was investigated using synthetic X-junctions. RecG dissociates X-junctions to flayed duplex products, although DNA...
K L Kindle
Proceedings of the National Academy of Sciences of the United States of America, 87(3), 1228-1232 (1990-02-01)
By using a method in which cell-wall-deficient Chlamydomonas reinhardtii cells were agitated in the presence of DNA, glass beads, and polyethylene glycol, nuclear transformation rates of approximately 10(3) transformants per micrograms of plasmid DNA were achieved. The nitrate reductase gene...
Tong Zhang et al.
PloS one, 7(8), e43872-e43872 (2012-09-07)
Crystal structures of Thermotoga maritima magnesium transporter CorA, reported in 2006, revealed its homo-pentameric constructions. However, the structure of the highly conserved extracellular interhelical loops remains unsolved, due to its high flexibility. We have explored the configurations of the loops...

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