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H8125

Sigma-Aldrich

L-Histidine monohydrochloride monohydrate

≥98% (HPLC)

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Synonym(s):
L-α-Amino-β-(4-imidazolyl)propionic acid monohydrochloride
Empirical Formula (Hill Notation):
C6H9N3O2 · HCl · H2O
CAS Number:
Molecular Weight:
209.63
Beilstein/REAXYS Number:
4168261
MDL number:
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.32

Quality Level

assay

≥98% (HPLC)

mp

254 °C (dec.) (lit.)

solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

SMILES string

O.Cl.N[C@@H](Cc1c[nH]cn1)C(O)=O

InChI

1S/C6H9N3O2.ClH.H2O/c7-5(6(10)11)1-4-2-8-3-9-4;;/h2-3,5H,1,7H2,(H,8,9)(H,10,11);1H;1H2/t5-;;/m0../s1

InChI key

CMXXUDSWGMGYLZ-XRIGFGBMSA-N

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1 of 4

This Item
H4036533701.04354
solubility

H2O: 50 mg/mL, clear, colorless to very faintly yellow

solubility

H2O: 50 mg/mL

solubility

H2O: 1 g/10 mL, clear, colorless (hot)

solubility

149.55 g/L

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

mp

254 °C (dec.) (lit.)

Application

L-Histidine monohydrochloride monohydrate has been used as a component of broth to match the tuna meat amino acid composition. It has also been used for partial rescue of the IMPL2 (myo-inositol monophosphatase) phenotype during seed development of Arabidopsis.

Biochem/physiol Actions

Histidine takes part in protein methylation. It is associated with the hemoglobin structure and function. Histidine is present in antioxidative dipeptides. It is involved in one-carbon unit metabolism.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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L-Histidine suitable for cell culture, meets EP, USP testing specifications, from non-animal source

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L-Histidine

Modelling the effect of temperature, carbon dioxide, water activity and pH on growth and histamine formation by Morganella psychrotolerans
Emborg J and Dalgaard P
International Journal of Food Microbiology, 128(2), 226-233 (2008)
Expression and functions of myo-inositol monophosphatase family genes in seed development of Arabidopsis
Sato Y, et al.
Journal of Plant Research, 124(3), 385-394 (2011)
Yuko Sato et al.
Journal of plant research, 124(3), 385-394 (2010-10-21)
Myo-inositol monophosphatase (IMP) catalyzes the dephosphorylation of myo-inositol 3-phosphate in the last step of myo-inositol biosynthesis. IMP is also important in phosphate metabolism and is required for the biosynthesis of cell wall polysaccharides, phytic acid, and phosphatidylinositol. In Arabidopsis, IMP
A Bennett et al.
The Journal of nutrition, 129(12), 2236-2238 (1999-11-26)
Boron is required for the growth of vascular plants and embryonic development in fish. The molecular basis of boron's essentiality, however, remains unknown for both. The objective of this study was to determine whether yeast (Saccharomyces cerevisiae) could be used
Garrett RH and Grisham CM
Biochemistry (2012)

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