H9279

Sigma-Aldrich

α-Hydroxyfarnesylphosphonic acid

2 mg/mL in ethanol

Empirical Formula (Hill Notation):
C15H27O4P
CAS Number:
Molecular Weight:
302.35
EC Number:
MDL number:
PubChem Substance ID:
Pricing and availability is not currently available.

concentration

2 mg/mL in ethanol

storage temp.

−20°C

SMILES string

C\C(C)=C\CC\C(C)=C\CC\C(C)=C\C(O)P(O)(O)=O

Biochem/physiol Actions

Inhibitor of farnesyltransferase; much weaker activity against geranylgeranyl transferase.

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Hazard Codes

F

Risk Statement

11

Safety Statement

7-16

RIDADR

UN1170 - class 3 - PG 2 - Ethanol, solution

WGK Germany

2

Flash Point(F)

57.2 °F

Flash Point(C)

14 °C

Certificate of Analysis
Certificate of Origin
J B Gibbs et al.
The Journal of biological chemistry, 268(11), 7617-7620 (1993-04-15)
The ras oncogene product, Ras, is synthesized in vivo as a precursor protein that requires post-translational processing to become biologically active and to be capable of transforming mammalian cells. Farnesylation appears to be a critical modification of Ras, and thus...

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