The solubility of H9377 has been tested at a concentration of 50 mg/ml in a mixture of 2 parts formic acid to 1 part water, equivalent to a 5% solution. While this may not represent the maximum solubility in the formic acid water mixture, it is the available data. The molecular weight of Hypoxanthine is 136.11 amu, and a 1M solution can be prepared by dissolving 136.11 grams in 1 liter of solvent, provided that there is a suitable solvent for dissolution. This amount can be scaled down to the desired volume. Aliquots should be stored at -20°C for up to 6 months.
H9377
Hypoxanthine
≥99.0%, synthetic (organic), powder
Synonym(s):
6-Hydroxypurine
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| Size/SKU | Availability | Price |
|---|---|---|
1 g | Available to ship TODAYfromMILWAUKEE | $72.60 |
5 g | Available to ship TODAYfromMILWAUKEE | $81.20 |
25 g | Available to ship TODAYfromMILWAUKEE | $124.00 |
100 g | Check Cart for Availability | $405.00 |
About This Item
Empirical Formula (Hill Notation):
C5H4N4O
CAS Number:
Molecular Weight:
136.11
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-697-3
MDL number:
Beilstein/REAXYS Number:
5811
Assay:
≥99.0%
Biological source:
synthetic (organic)
Form:
powder
$72.60
Available to ship TODAYDetails
Product Name
Hypoxanthine, ≥99.0%
biological source
synthetic (organic)
Quality Segment
assay
≥99.0%
form
powder
SMILES string
O=C1NC=Nc2nc[nH]c12
InChI
1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChI key
FDGQSTZJBFJUBT-UHFFFAOYSA-N
Application
Hypoxanthine has been used:
- to gavage mice and to evaluate the activity of xanthine oxidase (XO) in pasteurized whole milk in vivo in potassium oxonate (PO) -induced mouse model of hyperuricemia
- as a supplement in Iscove′s modified Dulbecco′s medium (IMDM) medium to cultivate in-vitro cell line (EL-1 cells)
- as a pure standard for the quantification of hypoxanthine in vitreous fluid sample using high-performance liquid chromatography-ultra-violet (HPLC-UV) for the estimation of post-mortem interval
Hypoxanthine is a nutrient additive for a variety of cell culture applications involving bacterial, parasite (Plasmodium falciparum) and animal cells. Hypoxanthine is a component of selection media used in hybridoma technologies.
Biochem/physiol Actions
Hypoxanthine acts as an intermediate in purine metabolism. It elicits a vital role as a 5′-base of the anticodon in a few transfer-RNAs. Though similar to guanine (Gua), it is devoid of the exocyclic amino group at C(2) position. It may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases.
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This Item | |||
|---|---|---|---|
| description ≥99.0% | description powder, BioReagent, suitable for cell culture | description United States Pharmacopeia (USP) Reference Standard | description European Pharmacopoeia (EP) Reference Standard |
| biological source synthetic (organic) | biological source - | biological source - | biological source - |
| Quality Level 200 | Quality Level 200 | Quality Level - | Quality Level - |
| form powder | form powder | form - | form - |
| assay ≥99.0% | assay ≥99% | assay - | assay - |
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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What are the instructions for preparing a 1M hypoxanthine stock solution?
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