Daopeng Yuan et al.
The Journal of biological chemistry, 288(30), 21667-21677 (2013-06-19)
Immunoglobulin E (IgE) antibodies play a fundamental role in allergic disease and are a target for therapeutic intervention. IgE functions principally through two receptors, FcεRI and CD23 (FcεRII). Minute amounts of allergen trigger mast cell or basophil degranulation by cross-linking...
Elevated serum sCD23 and sCD30 up to two decades prior to diagnosis associated with increased risk of non-Hodgkin lymphoma.
M P Purdue et al.
Leukemia, 29(6), 1429-1431 (2015-01-09)
R Carvalho-Gontijo et al.
Scandinavian journal of immunology, 81(6), 515-524 (2015-03-25)
In this study, we described, for the first time, specific aspects of an anti-Leishmania immune response in a Brazilian Xakriabá indigenous community. Induction of an intracellular NO pathway, triggered by the binding of IgE to CD23 receptor in IFN-γ/IL-4 cytokines...
T Laitinen et al.
American journal of respiratory and critical care medicine, 161(3 Pt 1), 700-706 (2000-03-11)
On the basis of studies with animal models, the gene for the low-affinity receptor for immunoglobulin E (IgE) (FCER2, CD23) has been implicated as a candidate for IgE-mediated allergic diseases and bronchial hyperreactivity, or related traits. Given evidence for genetic...
Marcia A Chan et al.
American journal of respiratory cell and molecular biology, 50(2), 263-269 (2013-09-10)
CD23 is the low-affinity Fc receptor for IgE. When expressed on B cells, CD23 appears to play a role in regulation of IgE synthesis. Polymorphisms within FCER2, the gene encoding CD23, have been associated with atopy, increased risk of exacerbations...