Anti-ZADH2 antibody produced in rabbit

enhanced validation

Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Anti-Zinc-binding alcohol dehydrogenase domain-containing protein 2
Human Protein Atlas Number:

biological source


Quality Level

antibody form

affinity isolated antibody

antibody product type

primary antibodies



product line

Prestige Antibodies® Powered by Atlas Antibodies


buffered aqueous glycerol solution

species reactivity



antibody small pack of 25 μL

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation


immunoblotting: 0.04-0.4 μg/mL
immunohistochemistry: 1:50-1:200

immunogen sequence




UniProt accession no.

shipped in

wet ice

storage temp.


Gene Information

human ... ZADH2(284273)

General description

The gene ZADH2 (zinc-binding alcohol dehydrogenase domain-containing protein 2) is mapped on human chromosome 18q22.3. It belongs to the prostaglandin reductase family. The protein contains a peroxisomal targeting signal and localizes to the peroxisomes.


Zinc-binding alcohol dehydrogenase domain-containing protein 2 recombinant protein epitope signature tag (PrEST)

Biochem/physiol Actions

ZADH2 (zinc-binding alcohol dehydrogenase domain-containing protein 2) is responsible for conversion of 15-keto-prostaglandin E2 to 13,14-dihydro-15-keto-prostaglandin E2. It controls PPARγ (peroxisome proliferator-activated receptor γ) activity and thereby regulates adipocyte differentiation.

Features and Benefits

Prestige Antibodies® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:
  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.


Corresponding Antigen APREST75503.

Physical form

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

Legal Information

Prestige Antibodies is a registered trademark of Sigma-Aldrich Co. LLC


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


NONH for all modes of transport

WGK Germany


Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Yu Xia et al.
Journal of proteomics, 84, 78-91 (2013-04-11)
Tetralogy of Fallot (TOF) results in chronic progressive right ventricular (RV) pressure overload and shunt hypoxemia. We investigated the global changes in the proteome of RV among infant patients with and without TOF to gain an insight into early RV...
Yu-Hsiang Yu et al.
Journal of lipid research, 54(9), 2391-2399 (2013-07-04)
Adipocyte differentiation is a multistep program under regulation by several factors. Peroxisome proliferator-activated receptor γ (PPARγ) serves as a master regulator of adipogenesis. However, the endogenous ligand for PPARγ remained elusive until 15-keto-PGE2 was identified recently as an endogenous PPARγ...
Sebastian Wiese et al.
Molecular & cellular proteomics : MCP, 6(12), 2045-2057 (2007-09-05)
The peroxisome represents a ubiquitous single membrane-bound key organelle that executes various metabolic pathways such as fatty acid degradation by alpha- and beta-oxidation, ether-phospholipid biosynthesis, metabolism of reactive oxygen species, and detoxification of glyoxylate in mammals. To fulfil this vast...

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